Microscale communication between bacterial pathogens and the host epithelium

AK Mix, G Goob, E Sontowski, CR Hauck - Genes & Immunity, 2021 - nature.com
Pathogenic bacteria have evolved a variety of highly selective adhesins allowing these
microbes to engage specific surface determinants of their eukaryotic host cells. Receptor …

Mechanisms of Pathogenic Escherichia coli Attachment to Meat

N Corcionivoschi, I Balta, D McCleery… - Foodborne …, 2024 - liebertpub.com
Escherichia coli are present in the human and animal microbiome as facultative anaerobes
and are viewed as an integral part of the whole gastrointestinal environment. In certain …

Reusable glycan microarrays using a microwave assisted wet-erase (MAWE) process

AY Mehta, CA Tilton, L Muerner, S von Gunten… - …, 2024 - academic.oup.com
Modern studies on binding of proteins to glycans commonly involve the use of synthetic
glycans and their derivatives in which a small amount of the material is covalently printed …

Polysaccharides from Vaccaria segetalis seeds reduce urinary tract infections by inhibiting the adhesion and invasion abilities of uropathogenic Escherichia coli

R Yao, X Mao, Y Xu, X Qiu, L Zhou, Y Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
The seeds of Vaccaria segetalis (Neck.) are from a traditional medicinal plant Garcke, also
called Wang-Bu-Liu-Xing in China. According to the Chinese Pharmacopoeia, the seeds of …

B4galnt2-mediated host glycosylation influences the susceptibility to Citrobacter rodentium infection

A Suwandi, KG Alvarez, A Galeev, N Steck… - Frontiers in …, 2022 - frontiersin.org
Histo-blood group antigens in the intestinal mucosa play important roles in host–microbe
interactions and modulate the susceptibility to enteric pathogens. The B4galnt2 gene …

Identifying FmlH lectin-binding small molecules for the prevention of Escherichia coli-induced urinary tract infections using hybrid fragment-based design and …

P Samanta, RJ Doerksen - Computers in Biology and Medicine, 2023 - Elsevier
Nearly 50% of women are affected by urinary tract infections (UTIs) during their lifetimes.
The most common agent to cause UTIs is Uropathogenic Escherichia coli (UPEC). UPEC …

[HTML][HTML] Bird immunobiological parameters in the dissemination of the biofilm-forming bacteria Escherichia coli

E Lenchenko, N Sachivkina, T Lobaeva, N Zhabo… - Veterinary …, 2023 - ncbi.nlm.nih.gov
Materials and Methods: Clinical, immunological, bacteriological, and histological studies
were conducted on 15-day-old white Leghorn birds (n= 20). The birds were divided into two …

Distinct ecological fitness factors coordinated by a conserved Escherichia coli regulator during systemic bloodstream infection

N O'Boyle, GR Douce, G Farrell… - Proceedings of the …, 2023 - National Acad Sciences
The ability of bacterial pathogens to adapt to host niches is driven by the carriage and
regulation of genes that benefit pathogenic lifestyles. Genes that encode virulence or fitness …

Synthesis of regioisomeric maltose-based Man/Glc glycoclusters to control glycoligand presentation in 3D space

SO Jaeschke, I Vom Sondern… - Organic & Biomolecular …, 2021 - pubs.rsc.org
The investigation of carbohydrate recognition in a natural environment suffers from the
complexity of overlapping functional effects such as multivalency and heteromultivalency …

The role of bacterial size, shape and surface in macrophage engulfment of uropathogenic E. coli cells

E Peterson, B Söderström, N Prins, GHB Le… - bioRxiv, 2022 - biorxiv.org
Uropathogenic Escherichia coli (UPEC) can undergo extensive filamentation in the host
during acute urinary tract infections (UTIs). It has been hypothesised that this morphological …