[HTML][HTML] Genetics factors in major depression disease
M Shadrina, EA Bondarenko, PA Slominsky - Frontiers in psychiatry, 2018 - frontiersin.org
Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology.
According to the World Health Organization, about 350 million people in the world are …
According to the World Health Organization, about 350 million people in the world are …
[HTML][HTML] Amygdala circuit substrates for stress adaptation and adversity
Brain systems that promote the maintenance of homeostasis in face of stress have
significant adaptive value. A growing body of work across species demonstrates a critical …
significant adaptive value. A growing body of work across species demonstrates a critical …
Depression, neuroimaging and connectomics: a selective overview
Depression is a multifactorial disorder with clinically heterogeneous features involving
disturbances of mood and cognitive function. Noninvasive neuroimaging studies have …
disturbances of mood and cognitive function. Noninvasive neuroimaging studies have …
Major depressive disorder: new clinical, neurobiological, and treatment perspectives
DJ Kupfer, E Frank, ML Phillips - The Lancet, 2012 - thelancet.com
In this Seminar we discuss developments from the past 5 years in the diagnosis,
neurobiology, and treatment of major depressive disorder. For diagnosis, psychiatric and …
neurobiology, and treatment of major depressive disorder. For diagnosis, psychiatric and …
Central role of the brain in stress and adaptation: links to socioeconomic status, health, and disease
BS McEwen, PJ Gianaros - Annals of the New York Academy of …, 2010 - Wiley Online Library
The brain is the key organ of stress reactivity, coping, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …
The neurobiology of depression and antidepressant action
P Willner, J Scheel-Krüger, C Belzung - Neuroscience & biobehavioral …, 2013 - Elsevier
We present a comprehensive overview of the neurobiology of unipolar major depression
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …
Stress-and allostasis-induced brain plasticity
BS McEwen, PJ Gianaros - Annual review of medicine, 2011 - annualreviews.org
The brain is the key organ of stress processes. It determines what individuals will experience
as stressful, it orchestrates how individuals will cope with stressful experiences, and it …
as stressful, it orchestrates how individuals will cope with stressful experiences, and it …
The molecular neurobiology of depression
V Krishnan, EJ Nestler - Nature, 2008 - nature.com
Unravelling the pathophysiology of depression is a unique challenge. Not only are
depressive syndromes heterogeneous and their aetiologies diverse, but symptoms such as …
depressive syndromes heterogeneous and their aetiologies diverse, but symptoms such as …
Molecular evidence for BDNF-and GABA-related dysfunctions in the amygdala of female subjects with major depression
JP Guilloux, G Douillard-Guilloux, R Kota, X Wang… - Molecular …, 2012 - nature.com
Women are twice as likely as men to develop major depressive disorder (MDD) and are
more prone to recurring episodes. Hence, we tested the hypothesis that the illness may …
more prone to recurring episodes. Hence, we tested the hypothesis that the illness may …
Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety
Individual risk markers for depression and anxiety disorders have been identified but the
explicit pathways that link genes and environment to these markers remain unknown. Here …
explicit pathways that link genes and environment to these markers remain unknown. Here …