Dominance refers to the effect of a heterozygous genotype relative to that of the two
homozygous genotypes. The degree of dominance of mutations for fitness can have a …

Simulation is a key tool in population genetics for both methods development and empirical
research, but producing simulations that recapitulate the main features of genomic datasets …

Typically much smaller in number than their mainland counterparts, island populations are
ideal systems to investigate genetic threats to small populations. The Svalbard reindeer …

Habitat loss and population fragmentation pose severe threats to biodiversity and the
survival of many species. Population isolation and the decline in effective population size …

Island ecosystems provide natural laboratories to assess the impacts of isolation on
population persistence. However, most studies of persistence have focused on a single …

A few iconic examples have proven the value of facilitated gene flow for counteracting
inbreeding depression and staving off extinction; yet, the practice is often not implemented …

Genomic data and Artificial Intelligence (AI) models will start to play an increasingly
important role in conservation biology. In a recent study, Wilder et al.(2023) analysed …

Many species are facing unprecedented population size declines and deterioration of their
environment. This exposes species to genomic erosion, which we define here as the …

The presence and impact of recessive lethal mutations have been widely documented in
diploid outcrossing species. However, precise estimates of the proportion of new mutations …

Wildlife populations are becoming increasingly fragmented by anthropogenic development.
Small and isolated populations often face an elevated risk of extinction, in part due to …