[HTML][HTML] SARS-CoV-2 mutations and their impact on diagnostics, therapeutics and vaccines

S Thakur, S Sasi, SG Pillai, A Nag, D Shukla… - Frontiers in …, 2022 - frontiersin.org
With the high rate of COVID-19 infections worldwide, the emergence of SARS-CoV-2
variants was inevitable. Several mutations have been identified in the SARS-CoV-2 …

[HTML][HTML] Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …

[HTML][HTML] Global landscape of SARS-CoV-2 mutations and conserved regions

MH Abbasian, M Mahmanzar, K Rahimian… - Journal of Translational …, 2023 - Springer
Background At the end of December 2019, a novel strain of Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) disease (COVID-19) has been identified in Wuhan …

[HTML][HTML] Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1

J Chai, Y Cai, C Pang, L Wang, S McSweeney… - Nature …, 2021 - nature.com
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has created global health and
economic emergencies. SARS-CoV-2 viruses promote their own spread and virulence by …

[HTML][HTML] Drug repurposing for COVID-19: A review and a novel strategy to identify new targets and potential drug candidates

L Rodrigues, R Bento Cunha, T Vassilevskaia… - Molecules, 2022 - mdpi.com
In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the causative agent of coronavirus disease 2019 (COVID-19) was first identified in the …

[HTML][HTML] SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development

S Zhou, P Lv, M Li, Z Chen, H Xin, S Reilly… - Biomedicine & …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating
global pandemic, which has seriously affected human health worldwide. The discovery of …

[HTML][HTML] Emerging SARS-CoV-2 variants: a review of its mutations, its implications and vaccine efficacy

S Ramesh, M Govindarajulu, RS Parise, L Neel… - Vaccines, 2021 - mdpi.com
The widespread increase in multiple severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) variants is causing a significant health concern in the United States and …

[HTML][HTML] Dysbiosis of oral and gut microbiomes in SARS-CoV-2 infected patients in Bangladesh: elucidating the role of opportunistic gut microbes

SM Rafiqul Islam, MJ Foysal, MN Hoque… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease-2019 (COVID-19) is an infectious disease caused by SARS-CoV-2
virus. The microbes inhabiting the oral cavity and gut might play crucial roles in maintaining …

[HTML][HTML] Coronaviruses in humans and animals: the role of bats in viral evolution

A El-Sayed, M Kamel - Environmental Science and Pollution Research, 2021 - Springer
Bats act as a natural reservoir for many viruses, including coronaviruses, and have played a
crucial epidemiological role in the emergence of many viral diseases. Coronaviruses have …

[HTML][HTML] COVID-19: comprehensive review on mutations and current vaccines

AV Hebbani, S Pulakuntla, P Pannuru… - Archives of …, 2022 - Springer
Viral outbreaks had been a threat for the human race for a long time. Several epidemics and
pandemics have been reported in the past with serious consequences on human health and …