Systematic review: gastric microbiota in health and disease

M Rajilic‐Stojanovic, C Figueiredo… - Alimentary …, 2020 - Wiley Online Library
Background Helicobacter pylori is the most infamous constituent of the gastric microbiota
and its presence is the strongest risk factor for gastric cancer and other gastroduodenal …

[HTML][HTML] Precancerous lesions of the stomach, gastric cancer and hereditary gastric cancer syndromes

I Gullo, F Grillo, L Mastracci, A Vanoli, F Carneiro… - Pathologica, 2020 - ncbi.nlm.nih.gov
Gastric cancer accounts for about 6% of cancers worldwide, being the fifth most frequently
diagnosed malignancy and the third leading cause of cancer related death. Gastric …

The gastric precancerous cascade

P Correa, MB Piazuelo - Journal of digestive diseases, 2012 - Wiley Online Library
Invasive gastric carcinoma is preceded by a cascade of precancerous lesions. The first
recognized histologic change is active chronic inflammation, which may persist as such: non …

Butyrate-producing Clostridium cluster XIVa species specifically colonize mucins in an in vitro gut model

P Van den Abbeele, C Belzer, M Goossens… - The ISME …, 2013 - academic.oup.com
The human gut is colonized by a complex microbiota with multiple benefits. Although the
surface-attached, mucosal microbiota has a unique composition and potential to influence …

Management of precancerous conditions and lesions in the stomach (MAPS): guideline from the European Society of Gastrointestinal Endoscopy (ESGE), European …

M Dinis-Ribeiro, M Areia, AC De Vries… - …, 2012 - thieme-connect.com
Atrophic gastritis, intestinal metaplasia, and epithelial dysplasia of the stomach are common
and are associated with an increased risk for gastric cancer. In the absence of guidelines …

Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil

Z Lei, IB Tan, K Das, N Deng, H Zouridis, S Pattison… - Gastroenterology, 2013 - Elsevier
Background & Aims Almost all gastric cancers are adenocarcinomas, which have
considerable heterogeneity among patients. We sought to identify subtypes of gastric …

Idiopathic pulmonary fibrosis: a genetic disease that involves mucociliary dysfunction of the peripheral airways

CM Evans, TE Fingerlin, MI Schwarz… - Physiological …, 2016 - journals.physiology.org
Idiopathic pulmonary fibrosis (IPF) is an incurable complex genetic disorder that is
associated with sequence changes in 7 genes (MUC5B, TERT, TERC, RTEL1, PARN …

Pathology of gastric intestinal metaplasia: clinical implications

P Correa, BM Piazuelo, KT Wilson - Official journal of the …, 2010 - journals.lww.com
Intestinal metaplasia (IM) of the gastric mucosa is a relatively frequent precancerous lesion
(1). The inclusion of IM in a gastric biopsy pathology report often creates uncertainty for the …

Alterations in glycosylation as biomarkers for cancer detection

CA Reis, H Osorio, L Silva, C Gomes… - Journal of clinical …, 2010 - jcp.bmj.com
Glycoconjugates constitute a major class of biomolecules which include glycoproteins,
glycosphingolipids and proteoglycans. Glycans are involved in several physiological and …

Mucins: Structural diversity, biosynthesis, its role in pathogenesis and as possible therapeutic targets

SS Dhanisha, C Guruvayoorappan, S Drishya… - Critical reviews in …, 2018 - Elsevier
Mucins are the main structural components of mucus that create a selective protective
barrier for epithelial surface and also execute wide range of other physiological functions …