RNA-targeted therapies represent a platform for drug discovery involving chemically
modified oligonucleotides, a wide range of cellular RNAs, and a novel target-binding motif …

MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …

Renal fibrosis, irrespective of its etiology, is a final common stage of almost all chronic
kidney diseases. Increased apoptosis, epithelial‐to‐mesenchymal transition, and …

This report explores the available curative molecules directed against hepatocellular
carcinoma (HCC). Limited efficiency as well as other drawbacks of existing molecules led to …

Phenotypic changes induced by extracellular vesicles have been implicated in
mesenchymal stromal cell–promoted recovery of AKI. MicroRNAs are potential candidates …

Background Researchers now have a new avenue to investigate when it comes to miRNA-
based therapeutics. miRNAs have the potential to be valuable biomarkers for disease …

Micro-ribonucleic acids (miRNAs) are important class of short regulatory RNA molecules
involved in regulation of several essential biological processes. In addition to Dicer and …

Numerous sophisticated high-throughput sequencing technologies have been developed
over the past decade, and these have enabled the discovery of a diverse catalog of small …

Eukaryotic cells produce several classes of long and small noncoding RNA (ncRNA). Many
DNA and RNA viruses synthesize their own ncRNAs. Like their host counterparts, viral …

MicroRNAs (miRNA) load onto AGO proteins to target mRNAs for translational repression or
degradation. However, miRNA degradation can be triggered when extensively base-paired …