[HTML][HTML] Evolution of cortical neurons supporting human cognition
Human cognitive abilities are generally thought to arise from cortical expansion over the
course of human brain evolution. In addition to increased neuron numbers, this cortical …
course of human brain evolution. In addition to increased neuron numbers, this cortical …
Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex
S Hunt, Y Leibner, EJ Mertens, N Barros-Zulaica… - Cerebral …, 2023 - academic.oup.com
Synaptic transmission constitutes the primary mode of communication between neurons. It is
extensively studied in rodent but not human neocortex. We characterized synaptic …
extensively studied in rodent but not human neocortex. We characterized synaptic …
Mapping thalamic innervation to individual L2/3 pyramidal neurons and modeling their 'readout'of visual input
The thalamus is the main gateway for sensory information from the periphery to the
mammalian cerebral cortex. A major conundrum has been the discrepancy between the …
mammalian cerebral cortex. A major conundrum has been the discrepancy between the …
HCN channels at the cell soma ensure the rapid electrical reactivity of fast-spiking interneurons in human neocortex
V Szegedi, E Bakos, S Furdan, BH Kovács… - PLoS …, 2023 - journals.plos.org
Accumulating evidence indicates that there are substantial species differences in the
properties of mammalian neurons, yet theories on circuit activity and information processing …
properties of mammalian neurons, yet theories on circuit activity and information processing …
A natural cortical axis connecting the outside and inside of the human brain
CC Hilgetag, A Goulas, JP Changeux - Network Neuroscience, 2022 - direct.mit.edu
What structural and connectivity features of the human brain help to explain the
extraordinary human cognitive abilities? We recently proposed a set of relevant connectomic …
extraordinary human cognitive abilities? We recently proposed a set of relevant connectomic …
Genes associated with cognitive ability and HAR show overlapping expression patterns in human cortical neuron types
SLW Driessens, AA Galakhova, DB Heyer… - Nature …, 2023 - nature.com
GWAS have identified numerous genes associated with human cognition but their cell type
expression profiles in the human brain are unknown. These genes overlap with human …
expression profiles in the human brain are unknown. These genes overlap with human …
Gray and White Matter Metrics Demonstrate Distinct and Complementary Prediction of Differences in Cognitive Performance in Children: Findings from ABCD (N …
Individual differences in cognitive performance in childhood are a key predictor of significant
life outcomes such as educational attainment and mental health. Differences in cognitive …
life outcomes such as educational attainment and mental health. Differences in cognitive …
Human voltage-gated Na+ and K+ channel properties underlie sustained fast AP signaling
Human cortical pyramidal neurons are large, have extensive dendritic trees, and yet have
unexpectedly fast input-output properties: Rapid subthreshold synaptic membrane potential …
unexpectedly fast input-output properties: Rapid subthreshold synaptic membrane potential …
Cortical thickness, gray matter volume, and cognitive performance: a crosssectional study of the moderating effects of age on their interrelationships
In a sample comprising younger, middle-aged, and older cognitively healthy adults (N=
375), we examined associations between mean cortical thickness, gray matter volume …
375), we examined associations between mean cortical thickness, gray matter volume …
Relationship between lifestyle proxies of cognitive reserve and cortical regions in older adults
Introduction With the rapid increase in the population over 65 years old, research on healthy
aging has become one of the priorities in the research community, looking for a cost …
aging has become one of the priorities in the research community, looking for a cost …