Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin—A mini-review
Hesperidin (Hsd) and its aglycone, hesperetin (Hst), are two flavonoids from citrus species
that have various biological properties. Over the past decade, a large number of papers …
that have various biological properties. Over the past decade, a large number of papers …
Endocannabinoids, cannabinoids and the regulation of anxiety
Cannabis has been used for hundreds of years, with its ability to dampen feelings of anxiety
often reported as a primary reason for use. Only recently has the specific role cannabinoids …
often reported as a primary reason for use. Only recently has the specific role cannabinoids …
TRPV1 in the central nervous system: synaptic plasticity, function, and pharmacological implications
JG Edwards - Capsaicin as a therapeutic molecule, 2014 - Springer
The function of TRPV1 in the peripheral nervous system is increasingly being investigated
for its anti-inflammatory and antinociceptive properties in an effort to find a novel target to …
for its anti-inflammatory and antinociceptive properties in an effort to find a novel target to …
Noopept attenuates diabetes-mediated neuropathic pain and oxidative hippocampal neurotoxicity via inhibition of TRPV1 channel in rats
Neuropathic pain and oxidative neurotoxicity are two adverse main actions of diabetes
mellitus (DM). The expression levels of calcium ion (Ca 2+) permeable TRPV1 channels are …
mellitus (DM). The expression levels of calcium ion (Ca 2+) permeable TRPV1 channels are …
[HTML][HTML] Crocin improved learning and memory impairments in streptozotocin-induced diabetic rats
E Tamaddonfard, AA Farshid… - Iranian journal of …, 2013 - ncbi.nlm.nih.gov
Objective (s): Crocin influences many biological functions including memory and learning.
The present study was aimed to investigate the effects of crocin on learning and memory …
The present study was aimed to investigate the effects of crocin on learning and memory …
[HTML][HTML] Cannabinoid modulation of the stressed hippocampus
FF Scarante, C Vila-Verde, VL Detoni… - Frontiers in molecular …, 2017 - frontiersin.org
Exposure to stressful situations is one of the risk factors for the precipitation of several
psychiatric disorders, including Major Depressive Disorder, Posttraumatic Stress Disorder …
psychiatric disorders, including Major Depressive Disorder, Posttraumatic Stress Disorder …
[HTML][HTML] Ventral hippocampal diacylglycerol lipase-alpha deletion decreases avoidance behaviors and alters excitation-inhibition balance
Abstract The endogenous cannabinoid, 2-arachidonoylglycerol (2-AG), plays a key role in
the regulation of anxiety-and stress-related behavioral phenotypes and may represent a …
the regulation of anxiety-and stress-related behavioral phenotypes and may represent a …
The endocannabinoid system and anxiety
The medical properties of Cannabis sativa is known for centuries. Since the discovery and
characterization of the endogenous cannabinoid system, several studies have evaluated …
characterization of the endogenous cannabinoid system, several studies have evaluated …
Central administration of GPR 55 receptor agonist and antagonist modulates anxiety‐related behaviors in rats
A Rahimi, A Hajizadeh Moghaddam… - Fundamental & …, 2015 - Wiley Online Library
Abstract G‐protein‐coupled receptor 55 (GPR 55) has been proposed as an atypical
cannabinoid receptor, which is activated by lysophosphatidylinositols and some synthetic or …
cannabinoid receptor, which is activated by lysophosphatidylinositols and some synthetic or …
[HTML][HTML] Increased TRPV1 channels and FosB protein expression are associated with chronic epileptic seizures and Anxiogenic-like behaviors in a preclinical model …
W Lazarini-Lopes, GK Silva-Cardoso… - Biomedicines, 2022 - mdpi.com
Epilepsies are neurological disorders characterized by chronic seizures and their related
neuropsychiatric comorbidities, such as anxiety. The Transient Receptor Potential Vanilloid …
neuropsychiatric comorbidities, such as anxiety. The Transient Receptor Potential Vanilloid …