Somatostatin and somatostatin-containing neurons in shaping neuronal activity and plasticity
M Liguz-Lecznar, J Urban-Ciecko… - Frontiers in neural circuits, 2016 - frontiersin.org
Since its discovery over four decades ago, somatostatin (SOM) receives growing scientific
and clinical interest. Being localized in the nervous system in a subset of interneurons …
and clinical interest. Being localized in the nervous system in a subset of interneurons …
Somatostatin, olfaction, and neurodegeneration
D Saiz-Sanchez, I Ubeda-Bañon… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's and Parkinson's diseases are the most prevalent neurodegenerative disorders
in aging. Hyposmia has been described as an early symptom that can precede cognitive …
in aging. Hyposmia has been described as an early symptom that can precede cognitive …
Sex and genotype differences in odor detection in the 3× Tg-AD and 5XFAD mouse models of Alzheimer's disease at 6 months of age
KM Roddick, AD Roberts, HM Schellinck… - Chemical …, 2016 - academic.oup.com
Deficits in odor identification and detection are early symptoms of Alzheimer's disease (AD).
Two transgenic mouse models of AD, the 5XFAD and the 3× Tg-AD mice and their wildtype …
Two transgenic mouse models of AD, the 5XFAD and the 3× Tg-AD mice and their wildtype …
Brain network remodelling reflects tau-related pathology prior to memory deficits in Thy-Tau22 mice
L Degiorgis, M Karatas, M Sourty, E Faivre, J Lamy… - Brain, 2020 - academic.oup.com
In Alzheimer's disease, the tauopathy is known as a major mechanism responsible for the
development of cognitive deficits. Early biomarkers of such affectations for …
development of cognitive deficits. Early biomarkers of such affectations for …
Somatostatin-IRES-Cre mice: between knockout and wild-type?
C Viollet, A Simon, V Tolle, A Labarthe… - Frontiers in …, 2017 - frontiersin.org
The neuropeptide somatostatin (SOM) is widely expressed in rodent brain and somatostatin-
IRES-Cre (SOM-cre) mouse strains are increasingly used to unravel the physiology of SOM …
IRES-Cre (SOM-cre) mouse strains are increasingly used to unravel the physiology of SOM …
Somatostatin serves a modulatory role in the mouse olfactory bulb: neuroanatomical and behavioral evidence
S Nocera, A Simon, O Fiquet, Y Chen… - Frontiers in Behavioral …, 2019 - frontiersin.org
Somatostatin (SOM) and somatostatin receptors (SSTR1–4) are present in all olfactory
structures, including the olfactory bulb (OB), where SOM modulates physiological gamma …
structures, including the olfactory bulb (OB), where SOM modulates physiological gamma …
Developmental profile of brain neprilysin expression correlates with olfactory behaviour of rats
DS Vasilev, NM Dubrovskaya, IA Zhuravin… - Journal of Molecular …, 2021 - Springer
Abstract A neuropeptidase, neprilysin (NEP), is a major amyloid (Aβ)-degrading enzyme
involved in the pathogenesis of Alzheimer's disease (AD). The olfactory system is affected …
involved in the pathogenesis of Alzheimer's disease (AD). The olfactory system is affected …
Perceptual learning deficits mediated by somatostatin releasing inhibitory interneurons of olfactory bulb in an early life stress mouse model
M Pardasani, AM Ramakrishnan, S Mahajan… - Molecular …, 2023 - nature.com
Early life adversity (ELA) causes aberrant functioning of neural circuits affecting the health of
an individual. While ELA-induced behavioural disorders resulting from sensory and …
an individual. While ELA-induced behavioural disorders resulting from sensory and …
The effect of odor enrichment on olfactory acuity: Olfactometric testing in mice using two mirror-molecular pairs
A Blount, DM Coppola - PLoS One, 2020 - journals.plos.org
Intelligent systems in nature like the mammalian nervous system benefit from adaptable
inputs that can tailor response profiles to their environment that varies in time and space …
inputs that can tailor response profiles to their environment that varies in time and space …
Aging decreases chorda-tympani nerve responses to NaCl and alters morphology of fungiform taste pores in rats
ZD Whiddon, ST Rynberg, TG Mast… - Chemical senses, 2018 - academic.oup.com
Sensory processing is susceptible to decline with age. The sense of taste is, however,
generally thought to be resistant to aging. We investigated how chorda-tympani nerve …
generally thought to be resistant to aging. We investigated how chorda-tympani nerve …