[HTML][HTML] Allogeneic hematopoietic stem cell transplantation for mixed or overlap myelodysplastic/myeloproliferative disorders

A Symeonidis, S Chondropoulos, E Verigou… - Frontiers in …, 2022 - frontiersin.org
Chronic myelomonocytic leukemia (CMML) and the remaining, less frequent hybrid, mixed,
or overlap myelodysplastic syndromes/myeloproliferative neoplasms (MDSs/MPNs) are …

Outcomes and molecular profile of oligomonocytic CMML support its consideration as the first stage in the CMML continuum

X Calvo, D Roman-Bravo, N Garcia-Gisbert… - Blood …, 2022 - ashpublications.org
Patients with oligomonocytic chronic myelomonocytic leukemia (OM-CMML) are currently
classified according to the 2017 World Health Organization myelodysplastic syndromes …

Natural history of chronic myelomonocytic leukemia treated with hypomethylating agents

A Alfonso, G Montalban‐Bravo… - American journal of …, 2017 - Wiley Online Library
Hypomethylating agents (HMA) are the most commonly used therapeutic intervention in
chronic myelomonocytic leukemia (CMML). Due to the lack of CMML‐specific clinical trials …

[HTML][HTML] ASXL1 plays an important role in erythropoiesis

H Shi, S Yamamoto, M Sheng, J Bai, P Zhang… - Scientific reports, 2016 - nature.com
ASXL1 mutations are found in a spectrum of myeloid malignancies with poor prognosis.
Recently, we reported that Asxl1+/− mice develop myelodysplastic syndrome (MDS) or MDS …

[HTML][HTML] Real-world data on chronic myelomonocytic leukemia: Clinical and molecular characteristics, treatment, emerging drugs, and patient outcomes

S Castaño-Díez, M López-Guerra, C Bosch-Castañeda… - Cancers, 2022 - mdpi.com
Simple Summary Chronic myelomonocytic leukemia (CMML) is an infrequent disease with
poor prognosis and risk of progression into acute myeloid leukemia (AML). Stem cell …

Models of prognostication in chronic myelomonocytic leukemia

F Onida - Current Hematologic Malignancy Reports, 2017 - Springer
Abstract Purpose of Review Within the group of the myelodysplastic/myeloproliferative
overlap neoplasms of the adult age, chronic myelomonocytic leukemia (CMML) is …

Prognostic scoring systems and comorbidities in chronic myelomonocytic leukaemia: a nationwide population‐based study

D Moreno Berggren, M Kjellander… - British Journal of …, 2021 - Wiley Online Library
Outcomes in chronic myelomonocytic leukaemia (CMML) are highly variable and may be
affected by comorbidity. Therefore, prognostic models and comorbidity indices are important …

Allogeneic hematopoietic stem cell transplantation for myelofibrosis and chronic myelomonocytic leukemia

N Kekre, VT Ho - American journal of hematology, 2016 - Wiley Online Library
The efficacy of hematopoietic stem cell transplantation (HSCT) is not well established in
Philadelphia chromosome negative myeloproliferative neoplasms (Ph‐MPNs). Without …

Management of adult patients with CMML undergoing allo-HCT: recommendations from the EBMT PH&G Committee

F Onida, N Gagelmann, Y Chalandon, G Kobbe… - Blood, 2024 - ashpublications.org
Chronic myelomonocytic leukemia (CMML) is a heterogeneous disease presenting with
either myeloproliferative or myelodysplastic features. Allogeneic hematopoietic cell …

[PDF][PDF] Real-world data on chronic myelomonocytic leukemia: clinical and molecular characteristics, treatment, emerging drugs, and patient outcomes. Cancers (Basel) …

S Castaño-Díez, M López-Guerra, C Bosch-Castañeda… - 2022 - core.ac.uk
Despite emerging molecular information on chronic myelomonocytic leukemia (CMML),
patient outcome remains unsatisfactory and little is known about the transformation to acute …