The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Sepsis is the leading cause of mortality in critically ill patients. In this pathological syndrome,
septic shock and sequential multiple organ failure correlate with poor outcome. The …

Ulcerative colitis (UC) is one of the major inflammatory disorders of the gastrointestinal tract.
α-Terpineol (αTL) is naturally present in several plants, and it belongs to the monoterpenes …

ATP-sensitive potassium (KATP) channels link membrane excitability to metabolism. They
are regulated by intracellular nucleotides and by other factors including membrane …

Intestinal inflammation alters the contractile activity of intestinal smooth muscle. Motility
disorders of the gastrointestinal tract are clinically important symptoms, because they are …

Multiple K+ channels are expressed in the respiratory epithelium lining airways and alveoli.
Of the three main classes [1) voltage-dependent or Ca2+-activated, 6-transmembrane …

Background & Aims: Clinical studies show that patients with irritable bowel syndrome and
colonic diseases frequently experience sensory and motor dysfunctions of the urinary …

Sepsis is an infection-induced inflammatory syndrome responsible for∼ 10% of all deaths
worldwide. While pathophysiological mechanisms remain to be fully unravelled, new …

Mesenteric lymphatic vessels actively transport lymph, immune cells, fat, and other
macromolecules from the intestine via a rhythmical contraction-relaxation process called …

The ATP-sensitive potassium channel (KATP) in mouse colonic smooth muscle cell is a
complex containing a pore-forming subunit (Kir6. 1) and a sulfonylurea receptor subunit …