Osteoarthritis (OA), is a major cause of severe joint pain, physical disability and quality of life
impairment in the aging population across the developed and developing world. Increased …

Osteoarthritis (OA) is a family of degenerative diseases affecting multiple joint tissues.
Despite the diverse etiology and pathogenesis of OA, increasing evidence suggests that …

The infrapatellar fat pad (IPFP) and synovium play essential roles in maintaining knee joint
homeostasis and in the progression of osteoarthritis (OA). The cellular and transcriptional …

Although aging has traditionally been viewed as the most important risk factor for
osteoarthritis (OA), an increasing amount of epidemiological evidence has highlighted the …

Metabolic syndrome-associated osteoarthritis : Current Opinion in Rheumatology Metabolic
syndrome-associated osteoarthritis : Current Opinion in Rheumatology Log in or Register …

Osteoarthritis (OA) has long been considered the unique consequence of a wear and tear
process leading to cartilage degradation. Indeed, it is true that excessive mechanical stress …

Metabolic syndrome-associated osteoarthritis (Met-OA) is a clinical phenotype defined by
the role of obesity and metabolic syndrome as risk factors and by chronic low-grade …

Inflammatory changes are observed in affected joints of osteoarthritis (OA) patients and are
thought to be involved in the pathology that develops along OA progression. This narrative …

OA is a complex disease involving mechanical, metabolic and inflammatory contributions to
its aetiology. A key risk factor, obesity, is becoming an increasing focus of research due to its …

Osteoarthritis (OA) is a prevalent progressive disease that frequently coexists with obesity.
For several decades, OA was thought to be the result of ageing and mechanical stress on …