The formulation of nanomedicines for treating tuberculosis
A Costa, M Pinheiro, J Magalhães, R Ribeiro… - Advanced drug delivery …, 2016 - Elsevier
Recent estimates indicate that tuberculosis (TB) is the leading cause of death worldwide,
alongside the human immunodeficiency virus (HIV) infection. The current treatment is …
alongside the human immunodeficiency virus (HIV) infection. The current treatment is …
Delivering drugs to the lungs: The history of repurposing in the treatment of respiratory diseases
SP Newman - Advanced drug delivery reviews, 2018 - Elsevier
The repurposing of drug delivery by the pulmonary route has been applied to treatment and
prophylaxis of an increasingly wide range of respiratory diseases. Repurposing has been …
prophylaxis of an increasingly wide range of respiratory diseases. Repurposing has been …
The role of bacterial biofilms in chronic infections
T Bjarnsholt - Apmis, 2013 - Wiley Online Library
Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …
100 years. These infections killed millions of people in previous centuries, but they have …
An inhalable theranostic system for local tuberculosis treatment containing an isoniazid loaded metal organic framework Fe-MIL-101-NH2—from raw MOF to drug …
G Wyszogrodzka-Gaweł, P Dorożyński, S Giovagnoli… - Pharmaceutics, 2019 - mdpi.com
The theranostic approach to local tuberculosis treatment allows drug delivery and imaging of
the lungs for a better control and personalization of antibiotic therapy. Metal-organic …
the lungs for a better control and personalization of antibiotic therapy. Metal-organic …
Dry powder inhalable formulations for anti-tubercular therapy
Tuberculosis (TB) is an intracellular infectious disease caused by the airborne bacterium,
Mycobacterium tuberculosis. Despite considerable research efforts, the treatment of TB …
Mycobacterium tuberculosis. Despite considerable research efforts, the treatment of TB …
High dose dry powder inhalers to overcome the challenges of tuberculosis treatment
Tuberculosis (TB) is a major global health burden. The emergence of the human
immunodeficiency virus (HIV) epidemic and drug resistance has complicated global TB …
immunodeficiency virus (HIV) epidemic and drug resistance has complicated global TB …
Inhaled dry powder formulations for treating tuberculosis
Tuberculosis is the second leading cause of death from infectious diseases. Although
antitubercular drugs have been traditionally administered orally, there is a growing interest …
antitubercular drugs have been traditionally administered orally, there is a growing interest …
Cationic inhalable particles for enhanced drug delivery to M. tuberculosis infected macrophages
Inhalable microparticle-based drug delivery platforms are being investigated extensively for
Tuberculosis (TB) treatment as they offer efficient deposition in lungs and improved …
Tuberculosis (TB) treatment as they offer efficient deposition in lungs and improved …
Nanoparticle-mediated macrophage targeting—a new inhalation therapy tackling tuberculosis
Despite the potent clinical efficacy of linezolid (LNZ) against drug-resistant tuberculosis, its
safety and tolerability remain of major concern. Our objective is to develop antitubercular …
safety and tolerability remain of major concern. Our objective is to develop antitubercular …
Opportunities and challenges for host-directed therapies in tuberculosis
Background: Tuberculosis (TB) ranks alongside the human immunodeficiency virus (HIV) as
cause of death due to an infectious disease. Recently, host-targeted therapies (HDT) have …
cause of death due to an infectious disease. Recently, host-targeted therapies (HDT) have …