[HTML][HTML] 3D-Printed Electrochemical Sensors: A Comprehensive Review of Clinical Analysis Applications

TCO Cândido, DN Silva, MMC Borges, TG Barbosa… - Analytica, 2024 - mdpi.com
Three-dimensional printing technology has emerged as a versatile and cost-effective
alternative for the fabrication of electrochemical sensors. To enhance sensor sensitivity and …

Aptamers: precision tools for diagnosing and treating infectious diseases

S Sujith, R Naresh, BU Srivisanth… - Frontiers in Cellular …, 2024 - frontiersin.org
Infectious diseases represent a significant global health challenge, with bacteria, fungi,
viruses, and parasitic protozoa being significant causative agents. The shared symptoms …

Selection of a novel cell-internalizing RNA aptamer specific for CD22 antigen in B cell acute lymphoblastic leukemia

D Ruiz-Ciancio, LH Lin, S Veeramani… - … Therapy-Nucleic Acids, 2023 - cell.com
Despite improvements in B cell acute lymphoblastic leukemia (B-ALL) treatment, a
significant number of patients experience relapse of the disease, resulting in poor prognosis …

Unlocking precision in aptamer engineering: a case study of the thrombin binding aptamer illustrates why modification size, quantity, and position matter

MT Murray, SD Wetmore - Nucleic Acids Research, 2024 - academic.oup.com
The thrombin binding aptamer (TBA) is a prototypical platform used to understand the impact
of chemically-modified nucleotides on aptamer stability and target affinity. To provide …

AptaTrans: a deep neural network for predicting aptamer-protein interaction using pretrained encoders

I Shin, K Kang, J Kim, S Sel, J Choi, JW Lee… - BMC …, 2023 - Springer
Background Aptamers, which are biomaterials comprised of single-stranded DNA/RNA that
form tertiary structures, have significant potential as next-generation materials, particularly …

Surfactant-regularized liquid crystal aptasensor for optical monitoring of prostate-specific antigen: Appropriate for health care monitoring

Z Khoshbin, H Zahraee, M Ramezani, M Alibolandi… - Microchemical …, 2023 - Elsevier
Background Highly sensitive and accurate monitoring of disease biomarkers is of substantial
importance for early clinical diagnostic aims. Prostate cancer is one of the most prevalent …

Unique quinoline orientations shape the modified aptamer to sclerostin for enhanced binding affinity and bone anabolic potential

A Gubu, Y Ma, S Yu, H Zhang, Z Chen, S Ni… - … Therapy-Nucleic Acids, 2024 - cell.com
Osteogenesis imperfecta (OI) is a rare genetic disease characterized by bone fragility and
bone formation. Sclerostin could negatively regulate bone formation by antagonizing the …

Evolution of high-affinity aptamer probe for label-free and probe conformation switch-based fluorescent biosensing of β-carotene in seaweeds

L Zhang, W Wang, K Wei, W Dong, S Wang… - Microchemical Journal, 2024 - Elsevier
Abstract β-Carotene is an important bioactive component showing great activities and
receiving great attention in recent years. The traditional methods for the accurate detection …

Selection of DNA aptamers for the aptamer-assisted magnetic capture of the purified xylanase from Aspergillus niger

A Düzel, B Bora, GÖ Özgen, S Evran - International Journal of Biological …, 2024 - Elsevier
Xylanases are a group of enzymes that catalyze the hydrolysis of xylan. Xylanases have
wide industrial applications, and they can produced by various organisms. In this study, we …

Structure Switching Aptamers Enhance Sensitivity and Specificity of Photonic Crystal-Based Sensors for RSV-G Protein Detection

I Kalsoom, K Shehzadi, M Irfan, L Qiu, Y Wang… - Biosensors and …, 2025 - Elsevier
Photonic crystal-based aptasensors for viral proteins detection offer the advantage of
producing visible readouts. However, they usually suffer from limited sensitivity and high non …