Publisher Summary The chapter introduces the mitogen-activated protein (MAP) kinase
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of …

SUMMARY A cascade of three protein kinases known as a mitogen-activated protein kinase
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …

The intracellular signal transduction pathway by which the yeast Saccharomyces cerevisiae
responds to the presence of peptide mating pheromone in its surroundings is one of the best …

Many cells are able to orient themselves in a non-uniform environment by responding to
localized cues. This leads to a polarized cellular response, where the cell can either grow or …

Cdc42p is an essential GTPase that belongs to the Rho/Rac subfamily of Ras-like GTPases.
These proteins act as molecular switches by responding to exogenous and/or endogenous …

The establishment of cell polarity is critical for the development of many organisms and for
the function of many cell types. A large number of studies of diverse organisms from yeast to …

▪ Abstract The actin cytoskeleton is a highly dynamic network composed of actin polymers
and a large variety of associated proteins. The main functions of the actin cytoskeleton are to …

▪ Abstract All cells have the capacity to evoke appropriate and measured responses to signal
molecules (such as peptide hormones), environmental changes, and other external stimuli …

Mitogen-activated protein kinase (MAPK) cascades and the calcium–calcineurin pathway
control fundamental aspects of fungal growth, development and reproduction. Core …

Cell polarization generally occurs along a single well-defined axis that is frequently
determined by environmental cues such as chemoattractant gradients or cell–cell contacts …