Deuterium‐and tritium‐labelled compounds: applications in the life sciences

J Atzrodt, V Derdau, WJ Kerr… - Angewandte chemie …, 2018 - Wiley Online Library
Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …

Fate of antibiotics in soil and their uptake by edible crops

M Pan, LM Chu - Science of the Total Environment, 2017 - Elsevier
Antibiotics are bioactive substances, and their use as human and animal medicines for
illness prevention, disease treatment and growth promotion has increased in recent …

Matrix effects and application of matrix effect factor

W Zhou, S Yang, PG Wang - Bioanalysis, 2017 - Taylor & Francis
Although, LC–MS is one of the most sensitive and selective analytical techniques, it often
suffers from matrix effects, especially when using ESI for analyzing extracts of complicated …

[HTML][HTML] Compensate for or minimize matrix effects? Strategies for overcoming matrix effects in liquid chromatography-mass spectrometry technique: a tutorial review

M Cortese, MR Gigliobianco, F Magnoni, R Censi… - Molecules, 2020 - mdpi.com
In recent decades, mass spectrometry techniques, particularly when combined with
separation methods such as high-performance liquid chromatography, have become …

[HTML][HTML] LC-MS/MS in the clinical laboratory–where to from here?

SKG Grebe, RJ Singh - The Clinical biochemist reviews, 2011 - ncbi.nlm.nih.gov
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has seen enormous growth
in clinical laboratories during the last 10–15 years. It offers analytical specificity superior to …

液相色谱-串联质谱检测兽药残留中的基质效应研究进展

王立琦, 贺利民, 曾振灵, 陈建新 - 质谱学报, 2011 - cqvip.com
液相色谱-串联质谱技术作为强有力的分析工具已被广泛应用于多个领域,
但其检测中的基质效应对测定结果准确性的影响需引起重视. 本文综述了液相色谱 …

Matrix effects demystified: Strategies for resolving challenges in analytical separations of complex samples

ML Williams, AA Olomukoro… - Journal of …, 2023 - Wiley Online Library
Matrix effects can significantly impede the accuracy, sensitivity, and reliability of separation
techniques presenting a formidable challenge to the analytical process. It is crucial to …

Supercritical fluid chromatography in pharmaceutical analysis

V Desfontaine, D Guillarme, E Francotte… - … of pharmaceutical and …, 2015 - Elsevier
In the last few years, there has been a resurgence of supercritical fluid chromatography
(SFC), which has been stimulated by the introduction of a new generation of instruments and …

Recent developments in liquid chromatography–mass spectrometry and related techniques

M Holčapek, R Jirásko, M Lísa - Journal of Chromatography A, 2012 - Elsevier
This review summarizes the state-of-art in liquid chromatography–mass spectrometry (LC–
MS) and related techniques with the main focus on recent developments in the last decade …

Mass spectrometry, review of the basics: ionization

H Awad, MM Khamis, A El-Aneed - Applied Spectroscopy Reviews, 2015 - Taylor & Francis
Mass spectrometry (MS) has become an integral tool in life sciences. The first step in MS
analysis is ion formation (ionization). Many ionization methods currently exist; electrospray …