Primary liver cancer, which is scientifically referred to as hepatocellular carcinoma (HCC), is
a significant concern in the field of global health. It has been demonstrated that conventional …

Recent research has illuminated the profound bidirectional communication between the
gastrointestinal tract and the brain, furthering our understanding of neurological ailments …

Obesity is defined as a dampness-heat syndrome in traditional Chinese medicine. Coptidis
Rhizoma is an herb used to clear heat and eliminate dampness in obesity and its …

Background The gut microbiota plays a critical role in regulating brain function through the
microbiome-gut-brain axis (MGBA). Dysbiosis of the gut microbiota is associated with …

Accumulating evidence suggests that berberine (BBR) exhibits anti‐cancer effects in
hepatocellular carcinoma (HCC). However, the mechanisms by which BBR regulates the …

Significance: Peroxisome proliferator-activated receptors (PPARs) have a moderately
preserved amino-terminal domain, an extremely preserved DNA-binding domain, an integral …

Non-alcoholic fatty liver disease (NAFLD) is a global metabolic disease with high
prevalence in both adults and children. Importantly, NAFLD is becoming the main cause of …

Hepatocellular carcinoma (HCC) holds a prominent position among global cancer types.
Classically, HCC manifests in individuals with a genetic predisposition when they encounter …

In recent years, cancer research has highlighted the role of disrupted microbiota in
carcinogenesis and cancer recurrence. However, microbiota may also interfere with drug …

Antioxidant-rich supplementation plays an essential role in the function of mammals' central
nervous system. However, no research has documented the effect of berberine (BER) …