[HTML][HTML] Current status of MALDI-TOF mass spectrometry in clinical microbiology

TY Hou, C Chiang-Ni, SH Teng - Journal of food and drug analysis, 2019 - Elsevier
Mass spectrometry (MS) is a type of analysis used to determine what molecules make up a
sample, based on the mass spectrum that are created by the ions. Mass spectrometers are …

Matrix-assisted laser desorption ionization–time of flight mass spectrometry: a fundamental shift in the routine practice of clinical microbiology

AE Clark, EJ Kaleta, A Arora… - Clinical microbiology …, 2013 - Am Soc Microbiol
Within the past decade, clinical microbiology laboratories experienced revolutionary
changes in the way in which microorganisms are identified, moving away from slow …

[HTML][HTML] Blood culture-based diagnosis of bacteraemia: state of the art

O Opota, A Croxatto, G Prod'Hom, G Greub - Clinical Microbiology and …, 2015 - Elsevier
Blood culture remains the best approach to identify the incriminating microorganisms when
a bloodstream infection is suspected, and to guarantee that the antimicrobial treatment is …

MALDI-TOF mass spectrometry for microorganism identification

TC Dingle, SM Butler-Wu - Clinics in laboratory medicine, 2013 - labmed.theclinics.com
The clinical microbiology laboratory plays a critical role in patient care by providing definitive
knowledge of the cause of infection and antimicrobial susceptibility data to physicians …

Matrix-assisted laser desorption ionization–time of flight mass spectrometry in clinical microbiology

R Patel - Clinical infectious diseases, 2013 - academic.oup.com
Despite widespread application of nucleic acid diagnostics, cultures remain integral in
modern laboratories. Because cultures detect a large number of organism types, it is unlikely …

[HTML][HTML] Diagnosis of bloodstream infections: an evolution of technologies towards accurate and rapid identification and antibiotic susceptibility testing

KC Tjandra, N Ram-Mohan, R Abe, MM Hashemi… - Antibiotics, 2022 - mdpi.com
Bloodstream infections (BSI) are a leading cause of death worldwide. The lack of timely and
reliable diagnostic practices is an ongoing issue for managing BSI. The current gold …

Staphylococcus Epidermidis as a Cause of Bacteremia

S Kleinschmidt, F Huygens, J Faoagali… - Future …, 2015 - Taylor & Francis
Staphylococcus epidermidis is a biofilm-producing commensal organism found ubiquitously
on human skin and mucous membranes, as well as on animals and in the environment …

Rapid identification of pathogens in positive blood culture of patients with sepsis: review and meta‐analysis of the performance of the sepsityper kit

NG Morgenthaler, M Kostrzewa - International journal of …, 2015 - Wiley Online Library
Sepsis is one of the leading causes of deaths, and rapid identification (ID) of blood stream
infection is mandatory to perform adequate antibiotic therapy. The advent of MALDI‐TOF …

[HTML][HTML] Raman spectroscopy—A novel method for identification and characterization of microbes on a single-cell level in clinical settings

K Rebrosova, O Samek, M Kizovsky… - Frontiers in Cellular …, 2022 - frontiersin.org
Rapid and accurate identification of pathogens causing infections is one of the biggest
challenges in medicine. Timely identification of causative agents and their antimicrobial …

[HTML][HTML] Rapid phenotypic methods to improve the diagnosis of bacterial bloodstream infections: meeting the challenge to reduce the time to result

G Dubourg, B Lamy, R Ruimy - Clinical Microbiology and Infection, 2018 - Elsevier
Background Administration of appropriate antimicrobial therapy is one of the key factors in
surviving bloodstream infections. Blood culture is currently the reference standard for …