New insights into cerebrovascular pathophysiology and hypertension

AJS Webb, DJ Werring - Stroke, 2022 - Am Heart Assoc
Despite advances in acute management and prevention of cerebrovascular disease, stroke
and vascular cognitive impairment together remain the world's leading cause of death and …

Hypertension in chronic kidney disease: What lies behind the scene

OZ Ameer - Frontiers in pharmacology, 2022 - frontiersin.org
Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …

Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled …

M Azizi, K Sanghvi, M Saxena, P Gosse, JP Reilly… - The Lancet, 2021 - thelancet.com
Background Endovascular renal denervation reduces blood pressure in patients with mild-to-
moderate hypertension, but its efficacy in patients with true resistant hypertension has not …

Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham …

M Böhm, K Kario, DE Kandzari, F Mahfoud, MA Weber… - The Lancet, 2020 - thelancet.com
Background Catheter-based renal denervation has significantly reduced blood pressure in
previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL …

Long-term outcomes after catheter-based renal artery denervation for resistant hypertension: final follow-up of the randomised SYMPLICITY HTN-3 Trial

DL Bhatt, M Vaduganathan, DE Kandzari, MB Leon… - The Lancet, 2022 - thelancet.com
Summary Background The SYMPLICITY HTN-3 (Renal Denervation in Patients With
Uncontrolled Hypertension) trial showed the safety but not efficacy of the Symplicity system …

Optimum and stepped care standardised antihypertensive treatment with or without renal denervation for resistant hypertension (DENERHTN): a multicentre, open …

M Azizi, M Sapoval, P Gosse, M Monge, G Bobrie… - The Lancet, 2015 - thelancet.com
Background Conflicting blood pressure-lowering effects of catheter-based renal artery
denervation have been reported in patients with resistant hypertension. We compared the …

Effect of exercise training on ambulatory blood pressure among patients with resistant hypertension: a randomized clinical trial

S Lopes, J Mesquita-Bastos, C Garcia… - JAMA …, 2021 - jamanetwork.com
Importance Limited evidence suggests exercise reduces blood pressure (BP) in individuals
with resistant hypertension, a clinical population with low responsiveness to drug therapy …

[HTML][HTML] 2015 guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the management of hypertension

CE Chiang, TD Wang, KC Ueng, TH Lin, HI Yeh… - Journal of the Chinese …, 2015 - Elsevier
It has been almost 5 years since the publication of the 2010 hypertension guidelines of the
Taiwan Society of Cardiology (TSOC). There is new evidence regarding the management of …

Randomized sham-controlled trial of renal sympathetic denervation in mild resistant hypertension

S Desch, T Okon, D Heinemann, K Kulle, K Röhnert… - …, 2015 - Am Heart Assoc
Few data are available with regard to the effectiveness of renal sympathetic denervation in
patients with resistant hypertension yet only mildly elevated blood pressure (BP). Patients …

12-month blood pressure results of catheter-based renal artery denervation for resistant hypertension: the SYMPLICITY HTN-3 trial

GL Bakris, RR Townsend, JM Flack, S Brar… - Journal of the American …, 2015 - jacc.org
Background: Results of the SYMPLICITY HTN-3 (Renal Denervation in Patients With
Uncontrolled Hypertension) trial confirmed the safety but not the efficacy of renal …