The ability of epithelial cells to organize through cell–cell adhesion into a functioning
epithelium serves the purpose of a tight epithelial protective barrier. Contacts between …

Claudins are a multigene transmembrane protein family comprising at least 27 members. In
gastrointestinal tract, claudins are mainly located in the intestinal epithelia; many types of …

A healthy indigenous intestinal microbiome is indispensable for intra-and extra-intestinal
human health. Since well-established factors such as diet and antibiotic use only explain …

Purpose of review Tight junctions (TJs) are specialized differentiations of epithelial and
endothelial cell membranes. TJs play an important role in the adhesion of cells and their …

Mucosal surface layers are the critical borders throughout epithelial membranes. These
epithelial cells segregate luminal material from external environments. However, mucosal …

Abstract The F11 Receptor (F11R), also called Junctional Adhesion Molecule-A (JAM-
A)(F11R/JAM-A), is a transmembrane glycoprotein of the immunoglobulin superfamily …

Epithelial-mesenchymal transition (EMT) is an important mechanism in cancer progression
and malignancy including colorectal cancer (CRC). Importantly, inflammatory mediators are …

The dysregulation of the tight junctions (TJs) protein claudin-7 is closely related to the
development and metastasis of colorectal cancer (CRC). The aim of this study was to …

Bladder cancer displays an aggressive phenotype in the muscle-invasive phase, and is
associated with a high mortality rate. Therefore, novel molecular therapeutic targets are …

The present study aimed to identify molecules associated with lymphovascular invasion
(LVI) and perineural invasion (PNI) and to examine their biological behavior in colorectal …