Echinococcosis is a zoonosis caused by cestodes of the genus Echinococcus (family
Taeniidae). This serious and near-cosmopolitan disease continues to be a significant public …

Helminth infections are responsible for a considerable public health burden, yet the current
drug armamentarium is small. Given the high cost of drug discovery and development, the …

Human cystic and alveolar echinococcosis are helmintic zoonotic diseases caused by
infections with the larval stages of the cestode parasites Echinococcus granulosus and E …

Diagnosis and treatment of alveolar echinococcosis remains a challenge for clinicians. The
updated WHO-recommendations aim to support decisions on diagnosis and treatment of …

The search for novel therapeutic options to cure alveolar echinococcosis (AE), due to the
metacestode of Echinococcus multilocularis, is ongoing, and these developments could also …

Triclabendazole (TCBZ) remains the drug of choice for treating infections of the liver fluke,
Fasciola hepatica in livestock and has become the main drug used to treat human cases of …

Abstract The World Health Organization estimated that more than 1.5 billion people are
infected with soil-transmitted helminths globally, and foodborne trematodiases in humans …

The current chemotherapeutical treatment against alveolar echinococcosis relies exclusively
on benzimidazoles, which are not parasiticidal and can induce severe toxicity. There are no …

Echinococcus granulosus and Echinococcus multilocularis are cestode parasites, of which
the metacestode (larval) stages cause the neglected diseases cystic echinococcosis (CE) …

The lethal disease alveolar echinococcosis (AE) is caused by the metacestode stage of the
fox tapeworm Echinococcus multilocularis. Current chemotherapeutical treatment of AE …