[HTML][HTML] CD4+ T cell memory
M Künzli, D Masopust - Nature immunology, 2023 - nature.com
Specialized subpopulations of CD4+ T cells survey major histocompatibility complex class II–
peptide complexes to control phagosomal infections, help B cells, regulate tissue …
peptide complexes to control phagosomal infections, help B cells, regulate tissue …
The evolving role of tissue-resident memory T cells in infections and cancer
S Yenyuwadee, JL Sanchez-Trincado Lopez… - Science …, 2022 - science.org
Resident memory T cells (TRM) form a distinct type of T memory cells that stably resides in
tissues. TRM form an integral part of the immune sensing network and have the ability to …
tissues. TRM form an integral part of the immune sensing network and have the ability to …
The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues
L Kok, D Masopust, TN Schumacher - Nature Reviews Immunology, 2022 - nature.com
CD8+ tissue resident memory T cells (TRM cells) are essential for immune defence against
pathogens and malignancies, and the molecular processes that lead to TRM cell formation …
pathogens and malignancies, and the molecular processes that lead to TRM cell formation …
Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity
Tissue-resident memory T (TRM) cells are non-recirculating cells that exist throughout the
body. Although TRM cells in various organs rely on common transcriptional networks to …
body. Although TRM cells in various organs rely on common transcriptional networks to …
Defining memory CD8 T cell
MD Martin, VP Badovinac - Frontiers in immunology, 2018 - frontiersin.org
CD8 T cells comprising the memory pool display considerable heterogeneity, with individual
cells differing in phenotype and function. This review will focus on our current understanding …
cells differing in phenotype and function. This review will focus on our current understanding …
Location, location, location: Tissue resident memory T cells in mice and humans
The discovery of T cells resident in diverse tissues has altered our understanding of
adaptive immunity to encompass site-specific responses mediated by tissue-adapted …
adaptive immunity to encompass site-specific responses mediated by tissue-adapted …
Developmental plasticity allows outside-in immune responses by resident memory T cells
Central memory T (TCM) cells patrol lymph nodes and perform conventional memory
responses on restimulation: proliferation, migration and differentiation into diverse T cell …
responses on restimulation: proliferation, migration and differentiation into diverse T cell …
[HTML][HTML] Tissue resident memory T cells in the respiratory tract
MZM Zheng, LM Wakim - Mucosal immunology, 2022 - Elsevier
Owing to their capacity to rapidly spread across the population, airborne pathogens
represent a significant risk to global health. Indeed, several of the past major global …
represent a significant risk to global health. Indeed, several of the past major global …
Tissue-resident T cells and other resident leukocytes
D Masopust, AG Soerens - Annual review of immunology, 2019 - annualreviews.org
Resident memory T (Trm) cells stably occupy tissues and cannot be sampled in superficial
venous blood. Trm cells are heterogeneous but collectively constitute the most abundant …
venous blood. Trm cells are heterogeneous but collectively constitute the most abundant …
Heterogenous populations of tissue-resident CD8+ T cells are generated in response to infection and malignancy
Tissue-resident memory CD8+ T cells (Trm) provide host protection through continuous
surveillance of non-lymphoid tissues. Using single-cell RNA-sequencing (scRNA-seq) and …
surveillance of non-lymphoid tissues. Using single-cell RNA-sequencing (scRNA-seq) and …