Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Lanthipeptides are ribosomally synthesized and post-translationally modified peptides
(RiPPs) that display a wide variety of biological activities, from antimicrobial to antiallodynic …

Covering: 1988 to 2012 This review presents recommended nomenclature for the
biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) …

Antimicrobial peptides (AMPs) are essential elements of thehost defense system.
Characterized by heterogenous structures and broad‐spectrumaction, they are promising …

Lantibiotics are gene-encoded peptides that contain intramolecular ring structures,
introduced through the thioether containing lanthionine and methyllanthionine residues. The …

The current need for antibiotics with novel target molecules has coincided with advances in
technical approaches for the structural and functional analysis of the lantibiotics, which are …

Aided by genome-mining strategies, knowledge of the prevalence and diversity of
ribosomally synthesized natural products (RNPs) is rapidly increasing. Among these are the …

The avalanche of genomic information in the past decade has revealed that natural product
biosynthesis using the ribosomal machinery is much more widespread than originally …

Probiotics are defined as nonpathogenic living microorganisms, including some commensal
bacterial flora, which have beneficial effects on host health and disease prevention and/or …

In this article we describe the production and screening of a genetically encoded library of
106 lanthipeptides in Escherichia coli using the substrate-tolerant lanthipeptide synthetase …