[HTML][HTML] SARS-CoV-2, COVID-19 and the aging immune system
JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …
particular risk for severe disease and death in older adults and in adults with age-related …
[PDF][PDF] Mucosal immune responses to infection and vaccination in the respiratory tract
The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study
Objective To estimate the effectiveness of the inactivated whole virus vaccine, CoronaVac
(Sinovac Biotech), against symptomatic covid-19 in the elderly population of São Paulo …
(Sinovac Biotech), against symptomatic covid-19 in the elderly population of São Paulo …
[HTML][HTML] COVID-19 and preexisting comorbidities: risks, synergies, and clinical outcomes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …
[HTML][HTML] Efficacy and safety of Paxlovid in severe adult patients with SARS-Cov-2 infection: a multicenter randomized controlled study
J Liu, X Pan, S Zhang, M Li, K Ma, C Fan… - The Lancet Regional …, 2023 - thelancet.com
Summary Background Nirmatrelvir plus ritonavir (Paxlovid) reduced the risk of
hospitalization or death by 89% in high-risk, ambulatory adults with COVID-19. We aimed at …
hospitalization or death by 89% in high-risk, ambulatory adults with COVID-19. We aimed at …
Elapsed time since BNT162b2 vaccine and risk of SARS-CoV-2 infection: test negative design study
Objectives To determine whether time elapsed since the second injection of the Pfizer-
BioNTech BNT162b2 mRNA vaccine was significantly associated with the risk of covid-19 …
BioNTech BNT162b2 mRNA vaccine was significantly associated with the risk of covid-19 …
[HTML][HTML] Long COVID: a review and proposed visualization of the complexity of long COVID
R Perumal, L Shunmugam, K Naidoo… - Frontiers in …, 2023 - frontiersin.org
Post-Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus–2 (SARS-CoV-2)
infection, or Long COVID, is a prevailing second pandemic with nearly 100 million affected …
infection, or Long COVID, is a prevailing second pandemic with nearly 100 million affected …
[HTML][HTML] Advances and gaps in SARS-CoV-2 infection models
C Muñoz-Fontela, L Widerspick, RA Albrecht… - PLoS …, 2022 - journals.plos.org
The global response to Coronavirus Disease 2019 (COVID-19) is now facing new
challenges such as vaccine inequity and the emergence of SARS-CoV-2 variants of concern …
challenges such as vaccine inequity and the emergence of SARS-CoV-2 variants of concern …
[HTML][HTML] Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19
S Druzak, E Iffrig, BR Roberts, T Zhang… - Nature …, 2023 - nature.com
The pathogenesis of multi-organ dysfunction associated with severe acute SARS-CoV-2
infection remains poorly understood. Endothelial damage and microvascular thrombosis …
infection remains poorly understood. Endothelial damage and microvascular thrombosis …
[HTML][HTML] Role of senescence and aging in SARS-CoV-2 infection and COVID-19 disease
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …