A renewed concept on the MAPK signaling pathway in cancers: Polyphenols as a choice of therapeutics
Abnormalities in the mitogen-activated protein kinase (MAPK) signaling pathway are a key
contributor to the carcinogenesis process and have therefore been implicated in several …
contributor to the carcinogenesis process and have therefore been implicated in several …
[HTML][HTML] An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways
Z Hu, Y Guan, W Hu, Z Xu, M Ishfaq - Iranian Journal of Basic …, 2022 - ncbi.nlm.nih.gov
The flavonoids, baicalin, and its aglycone baicalein possess multi-fold therapeutic properties
and are mainly found in the roots of Oroxylum indicum (L.) Kurz and Scutellaria baicalensis …
and are mainly found in the roots of Oroxylum indicum (L.) Kurz and Scutellaria baicalensis …
Baicalein induces apoptosis and autophagy of breast cancer cells via inhibiting PI3K/AKT pathway in vivo and vitro
W Yan, X Ma, X Zhao, S Zhang - Drug design, development and …, 2018 - Taylor & Francis
Purpose Baicalein, a widely used Chinese herbal medicine, has shown anticancer effects
on many types of human cancer cell lines. However, little is known about the underlying …
on many types of human cancer cell lines. However, little is known about the underlying …
[HTML][HTML] Deciphering the pharmacological mechanisms of Scutellaria baicalensis Georgi on oral leukoplakia by combining network pharmacology, molecular docking …
F Hou, Z Yu, YH Cheng, Y Liu, S Liang, F Zhang - Phytomedicine, 2022 - Elsevier
Background Oral leukoplakia (OLK), an uncharacterized pathological condition that occurs
as a white patch in the oral mucosa, is the most common precancerous condition. Scutellaria …
as a white patch in the oral mucosa, is the most common precancerous condition. Scutellaria …
Role of plant-derived active constituents in cancer treatment and their mechanisms of action
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …
one of the main causes of death worldwide. Although substantial progress has been made …
Therapeutic potential of Scutellaria baicalensis Georgi in lung cancer therapy
L Xiang, Y Gao, S Chen, J Sun, J Wu, X Meng - Phytomedicine, 2022 - Elsevier
Background Globally, lung cancer is the leading cause of cancer associated mortalities. The
current conventional chemotherapy remains the preferred treatment option for lung cancer …
current conventional chemotherapy remains the preferred treatment option for lung cancer …
A comprehensive and current review on the role of flavonoids in lung cancer–Experimental and theoretical approaches
Background It is well-known that flavonoids, which can be easily obtained from many fruits
and vegetables are widely preferred in the treatment of some important diseases. Some …
and vegetables are widely preferred in the treatment of some important diseases. Some …
Flavones: Six selected flavones and their related signaling pathways that induce apoptosis in cancer
SH Jeong, HH Kim, SE Ha, MY Park… - International Journal of …, 2022 - mdpi.com
Cancer is a horrific disease that, to date, has no cure. It is caused by various factors and
takes many lives. Apoptosis is a programmed cell death mechanism and if it does not …
takes many lives. Apoptosis is a programmed cell death mechanism and if it does not …
Baicalein: A review on its anti‐cancer effects and mechanisms in lung carcinoma
N Chandrashekar, A Pandi - Journal of Food Biochemistry, 2022 - Wiley Online Library
Plant‐derived flavonoids are reported to function as potential anti‐cancer agents against
different types of cancer. Baicalein (BE) is an important flavonoid found in the roots of …
different types of cancer. Baicalein (BE) is an important flavonoid found in the roots of …
The potential of baicalin to enhance neuroprotection and mitochondrial function in a human neuronal cell model
Baicalin is a flavone glycoside derived from flowering plants belonging to the Scutellaria
genus. Previous studies have reported baicalin's anti-inflammatory and neuroprotective …
genus. Previous studies have reported baicalin's anti-inflammatory and neuroprotective …