African Americans have the highest incidence and mortality rates of colorectal cancer (CRC)
of any ethnic group in the United States. Although some of these disparities can be …

Purpose. The increasing incidence of colorectal cancer (CRC) in the past three decades in
Iran has made it a major public health burden. This study aimed to report its epidemiologic …

Background: Traditional medicines with anti-diabetic effects are considered suitable
supplements to treat diabetes. Among medicinal herbs, Stevia Rebaudiana Bertoni is …

Some serrated polyps of the colorectum are likely preinvasive lesions, evolving through a
newly recognized serrated pathway to colorectal cancer. To assess possible risk and …

Background Genome-wide DNA hypomethylation plays a role in genomic instability and
carcinogenesis. LINE-1 (L1 retrotransposon) constitutes a substantial portion of the human …

Background: It is unknown if, after controlling for clinicopathologic variables and treatment,
racial disparities in colon cancer outcomes persist. Molecular marker analysis in North …

Background Mutations and promoters' methylation of a set of candidate cancer genes (CAN
genes) are associated with progression of colorectal cancer (CRC). We hypothesized that …

Background Colon cancer (CRC) development often includes chromosomal instability (CIN)
leading to amplifications and deletions of large DNA segments. Epidemiological, clinical …

Colorectal cancer is the third most prevalent malignancy in Western countries and a major
cause of death despite recent improvements in screening programs and early detection …

Background Comprehensive genomic sequencing (CGS) has the potential to revolutionize
precision medicine for cancer patients across the globe. However, to date large-scale …