Squalene monooxygenase: a journey to the heart of cholesterol synthesis

NK Chua, HW Coates, AJ Brown - Progress in lipid research, 2020 - Elsevier
Squalene monooxygenase (SM) is a vital sterol synthesis enzyme across eukaryotic life. In
yeast, it is a therapeutic target for treating certain fungal infections, and in mammals it is a …

Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation

X Zhang, K Lin, Y Li - Plant Physiology and Biochemistry, 2020 - Elsevier
Phytosterols are a group of sterols exclusive to plants and fungi, but are indispensable to
humans because of their medicinal and nutritional values. However, current raw materials …

Synaptotagmins at the endoplasmic reticulum–plasma membrane contact sites maintain diacylglycerol homeostasis during abiotic stress

N Ruiz-Lopez, J Pérez-Sancho, AE Del Valle… - The Plant …, 2021 - academic.oup.com
Endoplasmic reticulum–plasma membrane contact sites (ER–PM CS) play fundamental
roles in all eukaryotic cells. Arabidopsis thaliana mutants lacking the ER–PM protein tether …

The reference genome of Camellia chekiangoleosa provides insights into Camellia evolution and tea oil biosynthesis

T Shen, B Huang, M Xu, P Zhou, Z Ni… - Horticulture …, 2022 - academic.oup.com
Camellia oil extracted from Camellia seeds is rich in unsaturated fatty acids and secondary
metabolites beneficial to human health. However, no oil-tea tree genome has yet been …

A widespread alternative squalene epoxidase participates in eukaryote steroid biosynthesis

J Pollier, E Vancaester, U Kuzhiumparambil… - Nature …, 2019 - nature.com
Steroids are essential triterpenoid molecules that are present in all eukaryotes and modulate
the fluidity and flexibility of cell membranes. Steroids also serve as signalling molecules that …

Nt-acetylation-independent turnover of SQUALENE EPOXIDASE 1 by Arabidopsis DOA10-like E3 ligases

RD Etherington, M Bailey, JB Boyer… - Plant …, 2023 - academic.oup.com
Abstract The acetylation-dependent (Ac/) N-degron pathway degrades proteins through
recognition of their acetylated N-termini (Nt) by E3 ligases called Ac/N-recognins. To date …

Melatonin-induced transcriptome variation of rapeseed seedlings under salt stress

X Tan, W Long, L Zeng, X Ding, Y Cheng… - International Journal of …, 2019 - mdpi.com
Salt stress inhibits the production of all crop species, including rapeseed (Brassica napus
L.), the second most widely planted oil crop species. Although melatonin was confirmed to …

Recent advances in steroidal saponins biosynthesis and in vitro production

S Upadhyay, GS Jeena, Shikha, RK Shukla - Planta, 2018 - Springer
Main conclusion Steroidal saponins exhibited numerous pharmacological activities due to
the modification of their backbone by different cytochrome P450s (P450) and UDP …

[HTML][HTML] The scope of flavin-dependent reactions and processes in the model plant Arabidopsis thaliana

R Eggers, A Jammer, S Jha, B Kerschbaumer… - Phytochemistry, 2021 - Elsevier
Flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are utilized as
coenzymes in many biochemical reduction-oxidation reactions owing to the ability of the …

Physiological and transcriptome analysis of sugar beet reveals different mechanisms of response to neutral salt and alkaline salt stresses

G Geng, R Li, P Stevanato, C Lv, Z Lu, L Yu… - Frontiers in plant …, 2020 - frontiersin.org
The salinization and alkalization of soil are widespread environmental problems. Sugar beet
(B. vulgaris L.) is a moderately salt tolerant glycophyte, but little is known about the different …