Programmed cell death (PCD) control in plants: New insights from the Arabidopsis thaliana deathosome

F Valandro, PK Menguer, C Cabreira-Cagliari… - Plant Science, 2020 - Elsevier
Programmed cell death (PCD) is a genetically controlled process that leads to cell suicide in
both eukaryotic and prokaryotic organisms. In plants PCD occurs during development …

Cell death in plant immunity

E Pitsili, UJ Phukan, NS Coll - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
Pathogen recognition by the plant immune system leads to defense responses that are often
accompanied by a form of regulated cell death known as the hypersensitive response (HR) …

Detection of damage-activated metacaspase activity by western blot in plants

S Stael, LP Miller, AD Fernandez-Fernandez… - Plant proteases and …, 2022 - Springer
Metacaspases are cysteine proteases that are present in plants, protists, fungi, and bacteria.
Previously, we found that physical damage, eg, pinching with forceps or grinding on liquid …

Arabidopsis metacaspase MC1 localizes in stress granules, clears protein aggregates, and delays senescence

N Ruiz-Solaní, J Salguero-Linares, L Armengot… - The Plant …, 2023 - academic.oup.com
Stress granules (SGs) are highly conserved cytoplasmic condensates that assemble in
response to stress and contribute to maintaining protein homeostasis. These membraneless …

Plant proteases in the control of the hypersensitive response

J Salguero-Linares, NS Coll - Journal of experimental botany, 2019 - academic.oup.com
The hypersensitive response (HR) is a plant defence reaction triggered by activation of
immune receptors upon pathogen recognition. It results in rapid cell death at the attempted …

A comprehensive phylogenetic analysis of the serpin superfamily

MA Spence, MD Mortimer, AM Buckle… - Molecular Biology …, 2021 - academic.oup.com
Serine protease inhibitors (serpins) are found in all kingdoms of life and play essential roles
in multiple physiological processes. Owing to the diversity of the superfamily, phylogenetic …

Reassessing apoptosis in plants

M Dickman, B Williams, Y Li, P de Figueiredo… - Nature plants, 2017 - nature.com
Cell death can be driven by a genetically programmed signalling pathway known as
programmed cell death (PCD). In plants, PCD occurs during development as well as in …

Metacaspases versus caspases in development and cell fate regulation

EA Minina, NS Coll, H Tuominen… - Cell Death & …, 2017 - nature.com
Initially found to be critically involved in inflammation and apoptosis, caspases have since
then been implicated in the regulation of various signaling pathways in animals. How …

The prodomain of Arabidopsis metacaspase 2 positively regulates immune signaling mediated by pattern‐recognition receptors

D Wu, H Tian, F Xu, J Yang, W Feng, S Bell… - New …, 2024 - Wiley Online Library
Metacaspases (MCs) are structural homologs of mammalian caspases found in plants, fungi,
and protozoa. Type‐I MCs carry an N‐terminal prodomain, the function of which is unclear …

Plant proteases during developmental programmed cell death

RA Buono, R Hudecek… - Journal of Experimental …, 2019 - academic.oup.com
Proteases are among the key regulators of most forms of programmed cell death (PCD) in
animals. Many PCD processes have also been associated with protease expression or …