[HTML][HTML] Schistosomiasis—from immunopathology to vaccines
DP McManus, R Bergquist, P Cai… - Seminars in …, 2020 - Springer
Schistosomiasis (bilharzia) is a neglected tropical disease caused by trematode worms of
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …
Immunomodulation by helminth parasites: defining mechanisms and mediators
Epidemiological and interventional human studies, as well as experiments in animal
models, strongly indicate that helminth parasitic infections can confer protection from …
models, strongly indicate that helminth parasitic infections can confer protection from …
[HTML][HTML] Comparative genomics of the major parasitic worms
Nature genetics, 2019 - nature.com
Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating
chronic infections of humans and animals, decimate crop production and are a major …
chronic infections of humans and animals, decimate crop production and are a major …
[HTML][HTML] Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution
Lampreys are representatives of an ancient vertebrate lineage that diverged from our own∼
500 million years ago. By virtue of this deeply shared ancestry, the sea lamprey (P. marinus) …
500 million years ago. By virtue of this deeply shared ancestry, the sea lamprey (P. marinus) …
[HTML][HTML] A Systematically Improved High Quality Genome and Transcriptome of the Human Blood Fluke Schistosoma mansoni
AV Protasio, IJ Tsai, A Babbage, S Nichol… - PLoS neglected …, 2012 - journals.plos.org
Schistosomiasis is one of the most prevalent parasitic diseases, affecting millions of people
in developing countries. Amongst the human-infective species, Schistosoma mansoni is also …
in developing countries. Amongst the human-infective species, Schistosoma mansoni is also …
[HTML][HTML] The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution
K Cwiklinski, JP Dalton, PJ Dufresne, J La Course… - Genome biology, 2015 - Springer
Abstract Background The liver fluke Fasciola hepatica is a major pathogen of livestock
worldwide, causing huge economic losses to agriculture, as well as 2.4 million human …
worldwide, causing huge economic losses to agriculture, as well as 2.4 million human …
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor
B Everts, L Hussaarts, NN Driessen… - Journal of Experimental …, 2012 - rupress.org
Omega-1, a glycosylated T2 ribonuclease (RNase) secreted by Schistosoma mansoni eggs
and abundantly present in soluble egg antigen, has recently been shown to condition …
and abundantly present in soluble egg antigen, has recently been shown to condition …
Schistosomiasis elimination: lessons from the past guide the future
DJ Gray, DP McManus, Y Li, GM Williams… - The Lancet infectious …, 2010 - thelancet.com
Schistosomiasis is a major neglected tropical disease, with more than 200 million people
infected and close to 800 million at risk. The disease burden is estimated to exceed 70 …
infected and close to 800 million at risk. The disease burden is estimated to exceed 70 …
[HTML][HTML] Genome-wide analyses reveal a role for peptide hormones in planarian germline development
JJ Collins III, X Hou, EV Romanova, BG Lambrus… - PLoS …, 2010 - journals.plos.org
Bioactive peptides (ie, neuropeptides or peptide hormones) represent the largest class of
cell-cell signaling molecules in metazoans and are potent regulators of neural and …
cell-cell signaling molecules in metazoans and are potent regulators of neural and …
The read-across hypothesis and environmental risk assessment of pharmaceuticals
M Rand-Weaver, L Margiotta-Casaluci… - … science & technology, 2013 - ACS Publications
Pharmaceuticals in the environment have received increased attention over the past
decade, as they are ubiquitous in rivers and waterways. Concentrations are in sub-ng to low …
decade, as they are ubiquitous in rivers and waterways. Concentrations are in sub-ng to low …