Connexins in cardiovascular and neurovascular health and disease: pharmacological implications
Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …
hemichannels and as intercellular gap junction channels that directly connect cells. In the …
[HTML][HTML] Gap junctions
Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …
Gap junctions
DA Goodenough, DL Paul - Cold Spring Harbor …, 2009 - cshperspectives.cshlp.org
Gap junctions are aggregates of intercellular channels that permit direct cell–cell transfer of
ions and small molecules. Initially described as low-resistance ion pathways joining …
ions and small molecules. Initially described as low-resistance ion pathways joining …
Plasma membrane channels formed by connexins: their regulation and functions
JC Sáez, VM Berthoud, MC Branes… - Physiological …, 2003 - journals.physiology.org
Sáez, Juan C., Viviana M. Berthoud, María C. Brañes, Agustín D. Martínez, and Eric C.
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …
Connexin hemichannels in astrocytes: role in CNS disorders
LY Xing, T Yang, SS Cui, G Chen - Frontiers in molecular …, 2019 - frontiersin.org
In the central nervous system (CNS), astrocytes form networks interconnected by gap
junctions made from connexins of the subtypes Cx30 and Cx43. When unopposed by an …
junctions made from connexins of the subtypes Cx30 and Cx43. When unopposed by an …
Connexins in the heart: regulation, function and involvement in cardiac disease
A Rodríguez-Sinovas, JA Sánchez… - International journal of …, 2021 - mdpi.com
Connexins are a family of transmembrane proteins that play a key role in cardiac physiology.
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …
The effects of connexin phosphorylation on gap junctional communication
PD Lampe, AF Lau - The international journal of biochemistry & cell biology, 2004 - Elsevier
Gap junctions are specialized membrane domains composed of collections of channels that
directly connect neighboring cells providing for the cell-to-cell diffusion of small molecules …
directly connect neighboring cells providing for the cell-to-cell diffusion of small molecules …
Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in …
JE Contreras, HA Sánchez… - Proceedings of the …, 2002 - National Acad Sciences
Rat cortical astrocytes in pure culture are functionally coupled to neighboring cells via
connexin (Cx) 43 gap junctions under ordinary conditions. Small fluorescent molecules such …
connexin (Cx) 43 gap junctions under ordinary conditions. Small fluorescent molecules such …
Regulation of gap junctions by phosphorylation of connexins
PD Lampe, AF Lau - Archives of biochemistry and biophysics, 2000 - Elsevier
Gap junctions are a unique type of intercellular junction found in most animal cell types. Gap
junctions permit the intercellular passage of small molecules and have been implicated in …
junctions permit the intercellular passage of small molecules and have been implicated in …
[HTML][HTML] Connexin-based gap junction hemichannels: gating mechanisms
Connexins (Cxs) form hemichannels and gap junction channels. Each gap junction channel
is composed of two hemichannels, also termed connexons, one from each of the coupled …
is composed of two hemichannels, also termed connexons, one from each of the coupled …