Unraveling the gene expression networks governing cancer initiation and development is
essential while remains largely uncompleted. With the innovations in RNA-seq technologies …

Technological advances over the past decade have unraveled the remarkable complexity of
RNA. The identification of small peptides encoded by long non-coding RNAs (lncRNAs) as …

Novel classes of small and long non-coding RNAs (ncRNAs) are being characterized at a
rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture …

The tumour suppressor p53 is activated following genotoxic stress and regulates the
expression of target genes involved in the DNA damage response (DDR). The discovery that …

Most of the human genome is transcribed into non-coding RNAs (ncRNAs), which
encompass a heterogeneous family of transcripts including microRNAs (miRNAs), long …

Wild‐type p53 functions as a tumour suppressor while mutant p53 possesses oncogenic
potential. Until now it remains unclear how a single mutation can transform p53 into a …

Less than 3% of the human genome generates protein-coding transcripts; the majority, far
from being strewn with evolutionary “junk,” is dynamically transcribed into non (protein) …

Perfluorooctanoic acid (PFOA) is one of the most commonly used perfluorinated
compounds, and exposure to it has been associated with a number of adverse health …

Long noncoding RNAs (lncRNAs) make up a large proportion of transcriptome in
eukaryotes, and have been revealed with many regulatory functions in various biological …

Breast cancer is an aggressive silent disease, representing 11.7% of the diagnosed cancer
worldwide, and it is also a leading cause of death in Saudi Arabia. Consequently …