The incidence of inflammatory bowel diseases (IBD) emerged with Westernisation of dietary
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …

Over the past three decades, a considerable body of evidence has highlighted T cells as
pivotal culprits in the pathogenesis of psoriasis. This includes the association of psoriasis …

Research into the pathophysiology of psoriasis has shed light onto many fascinating
immunological interactions and underlying genetic constellations. Most prominent among …

Host defense peptides/proteins (HDP s), also known as antimicrobial peptides/proteins
(AMP s), are key molecules in the cutaneous innate immune system. AMP s/HDP s …

Abstract S100A8/A9, a heterodimer of the two calcium-binding proteins S100A8 and
S100A9, has emerged as an important proinflammatory mediator in acute and chronic …

The vast diversity of S100 proteins has demonstrated a multitude of biological correlations
with cell growth, cell differentiation and cell survival in numerous physiological and …

Calprotectin is a calcium binding protein produced by neutrophils and monocytes locally at
the site of inflammation in order to trigger the innate immunity receptors. This unique …

Antimicrobial peptides (AMPs) are small molecules produced by a myriad of cells and play
important roles not only in protecting against infections and sustaining skin barrier …

The pathognesis of psoriasis still remains not fully elucidated. Recent advances favor the
idea that interactions between innate and adaptive immune response drive inflammatory …

Recent studies have proven that the overall pathophysiology of pancreatitis involves not
only the pancreatic acinar cells but also duct cells, however, pancreatic duct contribution in …