Thrombus composition and efficacy of thrombolysis and thrombectomy in acute ischemic stroke

P Jolugbo, RAS Ariëns - Stroke, 2021 - Am Heart Assoc
Thrombi retrieved from patients with acute ischemic stroke are highly heterogeneous.
Recent data suggest that thrombus composition may impact on mechanical thrombectomy …

Thrombectomy for distal, medium vessel occlusions: a consensus statement on present knowledge and promising directions

JL Saver, R Chapot, R Agid, AE Hassan, AP Jadhav… - Stroke, 2020 - Am Heart Assoc
Endovascular thrombectomy (EVT) is well established as a highly effective treatment for
acute ischemic stroke (AIS) due to proximal, large vessel occlusions (PLVOs). With iterative …

Endovascular thrombectomy with or without intravenous alteplase in acute stroke

P Yang, Y Zhang, L Zhang, Y Zhang… - … England Journal of …, 2020 - Mass Medical Soc
Background In acute ischemic stroke, there is uncertainty regarding the benefit and risk of
administering intravenous alteplase before endovascular thrombectomy. Methods We …

[HTML][HTML] Hemorrhagic transformation after ischemic stroke: mechanisms and management

JM Hong, DS Kim, M Kim - Frontiers in Neurology, 2021 - frontiersin.org
Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead
to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed …

Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome: a systematic review

W Brinjikji, S Duffy, A Burrows, W Hacke… - Journal of …, 2017 - jnis.bmj.com
Background and purpose Studying the imaging and histopathologic characteristics of
thrombi in ischemic stroke could provide insights into stroke etiology and ideal treatment …

[HTML][HTML] Risk factors, pathophysiologic mechanisms, and potential treatment strategies of futile recanalization after endovascular therapy in acute ischemic stroke

G Deng, Y Chu, J Xiao, K Shang, LQ Zhou… - Aging and …, 2023 - ncbi.nlm.nih.gov
Endovascular therapy is the first-line treatment for acute ischemic stroke. However, studies
have shown that, even with the timely opening of occluded blood vessels, nearly half of all …

Direct mechanical thrombectomy versus combined intravenous and mechanical thrombectomy in large-artery anterior circulation stroke: a topical review

U Fischer, J Kaesmacher, V Mendes Pereira, R Chapot… - Stroke, 2017 - Am Heart Assoc
Fischer et al Mechanical Thrombectomy vs Bridging Thrombolysis 2913 and before EVT in
bridging patients. 19 Relevant recanalization rates before EVT in bridging patients were …

Bridging thrombolysis achieved better outcomes than direct thrombectomy after large vessel occlusion: an updated meta-analysis

Y Wang, X Wu, C Zhu, M Mossa-Basha, A Malhotra - Stroke, 2021 - Am Heart Assoc
The utility and necessity of pretreatment with intravenous thrombolysis (IVT) before
mechanical thrombectomy (MT) remains an issue of strong debate. This study aims to …

Direct mechanical thrombectomy in tPA-ineligible and-eligible patients versus the bridging approach: a meta-analysis

J Kaesmacher, P Mordasini, M Arnold… - Journal of …, 2019 - jnis.bmj.com
Background Whether pretreatment with intravenous thrombolysis prior to mechanical
thrombectomy (IVT+ MTE) adds additional benefit over direct mechanical thrombectomy …

Thrombectomy versus combined thrombolysis and thrombectomy in patients with acute stroke: a matched-control study

XU Tong, Y Wang, J Fiehler, CT Bauer, B Jia, X Zhang… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: A recent randomized controlled trial DIRECT-MT (Direct Intra-
Arterial Thrombectomy to Revascularize AIS Patients With Large Vessel Occlusion Efficiently …