Concise reviews: cancer stem cell targeted therapies: toward clinical success

A Desai, Y Yan, SL Gerson - Stem cells translational medicine, 2019 - academic.oup.com
Cancer stem cells (CSCs) are a subpopulation of cells within tumors that possess the stem
cell characteristics of self-renewal, quiescence, differentiation, and the ability to recapitulate …

Notch and Wnt dysregulation and its relevance for breast cancer and tumor initiation

EB Braune, A Seshire, U Lendahl - Biomedicines, 2018 - mdpi.com
Breast cancer is the second leading cause of cancer deaths among women in the world.
Treatment has been improved and, in combination with early detection, this has resulted in …

Feeling cold and other underestimated symptoms in breast cancer: anecdotes or individual profiles for advanced patient stratification?

O Golubnitschaja - EPMA Journal, 2017 - Springer
Breast cancer (BC) epidemic is recognised as being characteristic for the early twenty-first
century. BC is a multifactorial disease, and a spectrum of modifiable (preventable) factors …

Breast cancer and Flammer syndrome: any symptoms in common for prediction, prevention and personalised medical approach?

P Zubor, A Gondova, J Polivka Jr, P Kasajova… - EPMA Journal, 2017 - Springer
An epidemic scale of the breast cancer (BC) prevalence is actually recognised as the reality
of the early twenty-first century. Particularly alarming is that the sporadic BC (about 90% of …

SOX10 induced Nestin expression regulates cancer stem cell properties of TNBC cells

W Feng, S Liu, R Zhu, B Li, Z Zhu, J Yang… - … and biophysical research …, 2017 - Elsevier
The mechanisms modulating the cancer stem cell (CSC) properties of triple negative breast
cancer (TNBC) cells were not fully understood. In this study, we performed data mining in …

FGF8 promotes cell proliferation and resistance to EGFR inhibitors via upregulation of EGFR in human hepatocellular carcinoma cells

Y Pei, X Sun, X Guo, H Yin, L Wang… - Oncology …, 2017 - spandidos-publications.com
Abstract Fibroblast growth factor 8 (FGF8), a member of the fibroblast growth factor (FGF)
family, is upregulated in several human cancers, including HCC (HCC). Previous studies …

Targeting tumor microenvironment to curb chemoresistance via novel drug delivery strategies

C Bhavsar, M Momin, T Khan, A Omri - Expert Opinion on Drug …, 2018 - Taylor & Francis
Introduction: Tumor is a heterogeneous mass of malignant cells co-existing with non-
malignant cells. This co-existence evolves from the initial developmental stages of the tumor …

[PDF][PDF] Некоторые молекулярные и иммунологические факторы прогноза трижды негативного рака молочной железы

КС Титов, АМ Казаков, МА Барышникова… - Онкогинекология, 2019 - osors.ru
Заключение. Агрессивное течение и неблагоприятный прогноз при ТНРМЖ диктуют
необходимость в более глубоком изучении его биологических особенностей …

Emerging patterns and implications of breast cancer epigenetics: an update of the current knowledge

T Venkatesh, S Thankachan, SP Kabekkodu… - Epigenetics and …, 2021 - Elsevier
Epigenetics is a broad term used to encompass changes in gene expression which are not
associated with any changes in the DNA sequence. They are important for normal …

Targeting stemness: Implications for precision medicine in breast cancer

ZM Liang, Y Chen, ML Luo - Translational Research in Breast Cancer …, 2017 - Springer
The genomic landscape of breast cancer has been delineated in recent years. Advances in
molecular characterization and targeting strategies are making it feasible to integrate …