Organosilanes are of vital importance for modern human society, having found widespread
applications in functional materials, organic synthesis, drug discovery and life sciences …

The alkali metal tert‐butoxides have found wide application as catalysts and activators for
the conversion of numerous organic molecules. These formidable additives in catalytic …

The development of diagnostic devices relies heavily on the immobilization of biomolecules
on supportive substrates, that is the generation of interfaces that can thereafter produce a …

Iron‐catalyzed cascade silyl radical addition/6‐exo‐trig cyclization/dearomatization of biaryl
ynones has been developed. This approach uses silane as the precursor of silyl radical as …

The advent of flow chemistry and flow microreactor technology in organic synthesis has
added a series of options to the toolbox of synthetic chemists by enabling access to …

The direct C–H metallation of tetrahydrofuran (THF) to generate α-anionic THF is one of the
most straightforward methods for the functionalization of THF. However, the stability of THF …

Reactive organometallic intermediates present a distinct opportunity for the creation of novel
carbon-carbon and carbon-heteroatom bonds. Whereas their utility in synthesis is well …

Alkyllithium reagents represent one of the most commonly used organometallic compounds.
The wide range of applications results mostly from their ability to react as Brønsted bases …

This review aims to highlight the role of silicon in drug discovery. Silicon and carbon are
often regarded as being similar with silicon located directly beneath carbon in the same …

Continuous flow reactors have earned their place as an important technology in organic
synthesis, receiving increased interest in the past decade. The favorable heat and mass …