Magnesium (Mg) is involved in the regulation of metabolism and in the maintenance of the
homeostasis of all the tissues, including the brain, where it harmonizes nerve signal …

Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …

Status epilepticus (SE) is the maximal expression of epilepsy with a high morbidity and
mortality. It occurs due to the failure of mechanisms that terminate seizures. Both human and …

After 1h of lithium-pilocarpine status epilepticus (SE), immunocytochemical labeling of
NMDA receptor NR1 subunits reveals relocation of subunits from the interior to the cell …

Acquired epilepsies can arise as a consequence of brain injury and result in unprovoked
seizures that emerge after a latent period of epileptogenesis. These epilepsies pose a major …

Objective: A study was undertaken to characterize the plasticity of AMPA receptor (AMPAR)‐
mediated neurotransmission in the hippocampus during status epilepticus (SE). Methods …

The N-methyl-d-aspartate (NMDA) receptor plays an important role in the pathophysiology of
several neurological diseases, including epilepsy. The present study investigated the effect …

Ethnopharmacological relevance Temporal lobe epilepsy remains one of the most drug-
resistant focal epilepsy, leading to enormous healthcare burden. Among traditional herb …

The mechanisms underlying neuronal death following excessive activity such as occurs
during prolonged seizures are unclear, but mitochondrial dysfunction has been …

Clinical and experimental data hints that prolonged and repeated epileptic seizures can
lead to molecular, biochemical, metabolic, and structural changes in the brain, a continuous …