The biology and evolution of spider venoms

T Lüddecke, V Herzig, BM Von Reumont… - Biological …, 2022 - Wiley Online Library
Spiders are diverse, predatory arthropods that have inhabited Earth for around 400 million
years. They are well known for their complex venom systems that are used to overpower …

Versatile spider venom peptides and their medical and agricultural applications

NJ Saez, V Herzig - Toxicon, 2019 - Elsevier
Spiders have been evolving complex and diverse repertoires of peptides in their venoms
with vast pharmacological activities for more than 300 million years. Spiders use their …

Venom composition and strategies in spiders: is everything possible?

L Kuhn-Nentwig, R Stöcklin, W Nentwig - Advances in insect physiology, 2011 - Elsevier
This review on all spider venom components known by the end of 2010 bases on 1618
records for venom compounds from 174 spider species (= 0.41% of all known species) …

Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications

R Guo, G Guo, A Wang, G Xu, R Lai, H Jin - Molecules, 2023 - mdpi.com
Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity,
with 47,000 described species and an estimated 150,000 species in existence. Evolving …

Supramolecular Detoxification of Macromolecular Biotoxin through the Complexation by a Large‐Sized Macrocycle

L Zhao, J Chen, L Tian, Y Zhang, L Chen… - Advanced …, 2022 - Wiley Online Library
Biotoxins are diverse, complex, and hypertoxic, ultimately serving as grave and lasting
menaces to humanity. Here, it is aimed to introduce a new detoxification methodology for …

Latarcins: versatile spider venom peptides

PV Dubovskii, AA Vassilevski, SA Kozlov… - Cellular and Molecular …, 2015 - Springer
Arthropod venoms feature the presence of cytolytic peptides believed to act synergetically
with neurotoxins to paralyze prey or deter aggressors. Many of them are linear, ie, lack …

Insects, arachnids and centipedes venom: A powerful weapon against bacteria. A literature review

F Fratini, G Cilia, B Turchi, A Felicioli - Toxicon, 2017 - Elsevier
Currently, new antimicrobial molecules extracted or obtained by natural sources, could be a
valide alternative to traditional antibiotics. Most of these molecules are represented by …

PEGylation of the antimicrobial peptide LyeTx Ib maintains structure-related biological properties and improves selectivity

JC Moreira Brito, LR Carvalho… - Frontiers in Molecular …, 2022 - frontiersin.org
The biological activity of antimicrobial peptides and proteins is closely related to their
structural aspects and is sensitive to certain post-translational modifications such as …

Insights into antimicrobial peptides from spiders and scorpions

X Wang, G Wang - Protein and peptide letters, 2016 - ingentaconnect.com
The venoms of spiders and scorpions contain a variety of chemical compounds.
Antimicrobial peptides (AMPs) from these organisms were first discovered in the 1990s. As …

Animal venom peptides: potential for new antimicrobial agents

M Primon-Barros, A José Macedo - Current topics in medicinal …, 2017 - ingentaconnect.com
Microbial infections affect people worldwide, causing diseases with significant impact on
public health, indicating the need for research and development of new antimicrobial …