As one of the highest energy consumer organ in mammals, the heart has to be provided with
a high amount of energy as soon as its first beats in utero. During the development of this …

That cancer cells show patterns of metabolism different from normal cells has been known
for over 50 years. Yet, it is only in the past decade or so that an appreciation of the benefits …

Neonatal heart undergoes metabolic conversion and cell cycle arrest preparing for the
increased workload during adulthood. Herein, we report that neonatal ketone body elevation …

Dysregulated metabolism is an emerging hallmark of cancer, and there is abundant interest
in developing therapies to selectively target these aberrant metabolic phenotypes. Sitting at …

While gene regulatory networks involved in cardiogenesis have been characterized, the role
of bioenergetics remains less studied. Here we show that until midgestation, myocardial …

The past decade has witnessed a number of exciting developments in the field of
mitochondrial dynamics–a phenomenon in which changes in mitochondrial shape and …

Adult Consequences of Extremely Preterm Birth - Clinics in Perinatology Skip to Main Content
Skip to Main Menu Clinics in Perinatology Log in Register Log in Subscribe Claim Main menu …

Cellular oxidative stress results from the increased generation of reactive oxygen species
and/or the dysfunction of the antioxidant systems. Most intracellular reactive oxygen species …

Manifestations of cardiovascular diseases (CVDs) in a patient or a population differ based
on inherent biological makeup, lifestyle, and exposure to environmental risk factors. These …

Background The molecular mechanisms mediating postnatal loss of cardiac regeneration in
mammals are not fully understood. We aimed to provide an integrated resource of mRNA …