Longitudinal clinical–pathological studies have increasingly recognized the importance of
mixed pathologies (the coexistence of one or more neurodegenerative and cerebrovascular …

The global burden of ischaemic strokes is almost 4-fold greater than haemorrhagic strokes.
Current evidence suggests that 25–30% of ischaemic stroke survivors develop immediate or …

This paper is a proposal for an update on the characterization of cognitive impairments
associated with sporadic cerebral small vessel disease (SVD). We pose a series of …

Neurodegenerative disorders leading to dementia are common diseases that affect many
older and some young adults. Neuroimaging methods are important tools for assessing and …

Introduction This systematic review synthesizes current evidence for associations between
cortical amyloid β, visualized on amyloid positron emission tomography imaging, and white …

Many neuropsychological tests of executive functioning (EF) have test–retest reliabilities
below what is considered acceptable. Combining several tests into a composite can improve …

Cerebrovascular diseases are well established causes of cognitive impairment. Different
etiologic entities, such as vascular dementia (VaD), vascular cognitive impairment …

Purpose To validate the diagnostic performance of commercially available, deep learning-
based automatic white matter hyperintensity (WMH) segmentation algorithm for classifying …

Dementia is a global growing concern, affecting over 35 million people with a global
economic impact of over $604 billion US. With an ageing population the number of people …

Vascular dementia (VaD) is a history-laden disease entity that dates back to the 19th century
when arteriosclerotic brain atrophy due to hardening of the arteries was perceived as the …