Sino-nasal disease is appropriately treated with topical treatment, where the nasal mucosa
acts as a barrier to systemic absorption. Non-invasive nasal delivery of drugs has produced …

Inhalation exposes individuals to a diverse range of airborne particles carrying potential
health risks. Airflow and particle transport behavior is highly sensitive to airway geometry …

The standard multi-dose nasal spray pump features an integrated actuator and nozzle,
which inevitably causes a retraction of the nozzle tip during application. The retraction stroke …

Investigations on airborne transmission of pathogens constitute a rapidly expanding field,
primarily focused on understanding the expulsion patterns of respiratory particulates from …

Localized vortices can have significant influence on transport of inhaled particles through
the upper respiratory tract. These vortices have complex three-dimensional structure with …

Inhalation directs air through a defined pathway, initiating from nostrils, moving through the
main nasal cavity, past the pharynx and trachea, and culminating in the lungs. Inhaled …

This thesis aims to explore efficient drug delivery to clinical target sites along the human
upper airway that strongly depends on variables associated with the delivery device and the …

This research undertook an interdisciplinary approach, integrating bioengineering,
microbiology, molecular biology, and systems biology to investigate bacterial dynamics …

Delivery of drugs through the nasal route provides an alternative, yet highly efficacious
modality for administering both large and small pharmaceutic molecules. This method …