[HTML][HTML] Emerging roles of lysophospholipids in health and disease
ST Tan, T Ramesh, XR Toh, LN Nguyen - Progress in Lipid Research, 2020 - Elsevier
Lipids are abundant and play essential roles in human health and disease. The main
functions of lipids are building blocks for membrane biogenesis. However, lipids are also …
functions of lipids are building blocks for membrane biogenesis. However, lipids are also …
[HTML][HTML] LPA receptor signaling: pharmacology, physiology, and pathophysiology
Lysophosphatidic acid (LPA) is a small ubiquitous lipid found in vertebrate and
nonvertebrate organisms that mediates diverse biological actions and demonstrates …
nonvertebrate organisms that mediates diverse biological actions and demonstrates …
LPA receptors: subtypes and biological actions
Lysophosphatidic acid (LPA) is a small, ubiquitous phospholipid that acts as an extracellular
signaling molecule by binding to and activating at least five known G protein–coupled …
signaling molecule by binding to and activating at least five known G protein–coupled …
The emerging role of lysophosphatidic acid in cancer
GB Mills, WH Moolenaar - Nature Reviews Cancer, 2003 - nature.com
The bioactive phospholipid lysophosphatidic acid (LPA) stimulates cell proliferation,
migration and survival by acting on its cognate G-protein-coupled receptors. Aberrant LPA …
migration and survival by acting on its cognate G-protein-coupled receptors. Aberrant LPA …
The sponge microbiome project
Rhododendron delavayi Franch. is globally famous as an ornamental plant. Its distribution in
southwest China covers several different habitats and environments. However, not much …
southwest China covers several different habitats and environments. However, not much …
Lysophospholipid receptors: signaling and biology
▪ Abstract Lysophospholipids (LPs), such as lysophosphatidic acid and sphingosine 1-
phosphate, are membrane-derived bioactive lipid mediators. LPs can affect fundamental …
phosphate, are membrane-derived bioactive lipid mediators. LPs can affect fundamental …
[PDF][PDF] Lipidomics profiling reveals the role of glycerophospholipid metabolism in psoriasis
Psoriasis is a common and chronic inflammatory skin disease that is complicated by gene–
environment interactions. Although genomic, transcriptomic, and proteomic analyses have …
environment interactions. Although genomic, transcriptomic, and proteomic analyses have …
Two pathways for lysophosphatidic acid production
Lysophosphatidic acid (LPA, 1-or 2-acyl-sn-glycerol 3-phosphate) is a simple phospholipid
but displays an intriguing cell biology that is mediated via interactions with G protein …
but displays an intriguing cell biology that is mediated via interactions with G protein …
Lysophosphatidic acid as a lipid mediator with multiple biological actions
S Aikawa, T Hashimoto, K Kano… - The journal of …, 2015 - academic.oup.com
Lysophosphatidic acid (LPA) is one of the simplest glycerophospholipids with one fatty acid
chain and a phosphate group as a polar head. Although LPA had been viewed just as a …
chain and a phosphate group as a polar head. Although LPA had been viewed just as a …
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist
TM McIntyre, AV Pontsler, AR Silva… - Proceedings of the …, 2003 - National Acad Sciences
Lysophosphatidic acid (LPA) is a pluripotent lipid mediator acting through plasma
membrane-associated LPAx receptors that transduce many, but not all, of its effects. We …
membrane-associated LPAx receptors that transduce many, but not all, of its effects. We …