The emerging role of neutrophil extracellular traps (NETs) in tumor progression and metastasis

MT Masucci, M Minopoli, S Del Vecchio… - Frontiers in …, 2020 - frontiersin.org
Neutrophil Extracellular Traps (NETs) are net-like structures composed of DNA-histone
complexes and proteins released by activated neutrophils. In addition to their key role in the …

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

L Galluzzi, I Vitale, SA Aaronson, JM Abrams… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

The molecular machinery of regulated cell death

D Tang, R Kang, TV Berghe, P Vandenabeele… - Cell research, 2019 - nature.com
Cells may die from accidental cell death (ACD) or regulated cell death (RCD). ACD is a
biologically uncontrolled process, whereas RCD involves tightly structured signaling …

Programmed cell death as a defence against infection

I Jorgensen, M Rayamajhi, EA Miao - Nature reviews immunology, 2017 - nature.com
Eukaryotic cells can die from physical trauma, which results in necrosis. Alternatively, they
can die through programmed cell death upon the stimulation of specific signalling pathways …

Diverse stimuli engage different neutrophil extracellular trap pathways

EF Kenny, A Herzig, R Krüger, A Muth, S Mondal… - Elife, 2017 - elifesciences.org
Neutrophils release neutrophil extracellular traps (NETs) which ensnare pathogens and
have pathogenic functions in diverse diseases. We examined the NETosis pathways …

Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease

K Prame Kumar, AJ Nicholls, CHY Wong - Cell and tissue research, 2018 - Springer
Neutrophils are becoming recognized as highly versatile and sophisticated cells that display
de novo synthetic capacity and potentially prolonged lifespan. Emerging concepts such as …

The role of neutrophil extracellular traps in acute lung injury

D Scozzi, F Liao, AS Krupnick, D Kreisel… - Frontiers in …, 2022 - frontiersin.org
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …

Resolution of inflammation: a new therapeutic frontier

JN Fullerton, DW Gilroy - Nature reviews Drug discovery, 2016 - nature.com
Dysregulated inflammation is a central pathological process in diverse disease states.
Traditionally, therapeutic approaches have sought to modulate the pro-or anti-inflammatory …

Why traditional herbal medicine promotes wound healing: Research from immune response, wound microbiome to controlled delivery

Z Xu, M Dong, S Yin, J Dong, M Zhang, R Tian… - Advanced Drug Delivery …, 2023 - Elsevier
Impaired wound healing in chronic wounds has been a significant challenge for clinicians
and researchers for decades. Traditional herbal medicine (THM) has a long history of …

[HTML][HTML] Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

JD Dunn, LAJ Alvarez, X Zhang, T Soldati - Redox biology, 2015 - Elsevier
Reactive oxygen species (ROS) are integral components of multiple cellular pathways even
though excessive or inappropriately localized ROS damage cells. ROS function as anti …