Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus are both common
commensals and major opportunistic human pathogens. In recent decades, these bacteria …

Antimicrobial drug resistance is one of the major threats to global health. It has made
common infections increasingly difficult or impossible to treat, and leads to higher medical …

Fosfomycin is being increasingly prescribed for multidrug-resistant bacterial infections. In
patients with systemic involvement, intravenous fosfomycin is usually administered as a …

Background and Aim: The predominant species of the Enterococcus, Enterococcus faecalis
(E. faecalis) and Enterococcus faecium (E. faecium) cause great variety of infections …

The prevalence of enterococcal infection, especially E. faecium, is increasing, and the issue
of the impact of vancomycin resistance on clinical outcomes is controversial. This study …

Background Linezolid, an oxazolidinone antibiotic, is recommended for vancomycin-
resistant enterococci (VRE). However, 100% free-drug concentration above the minimum …

The optimal therapy for severe infections caused by vancomycin-resistant Enterococcus
faecium (VREfm) remains unclear, but the combination of linezolid and fosfomycin may be a …

Antimicrobial resistance (AMR) plays an important role in the pathogenesis and spread of
Clostridioides difficile infection (CDI). Many antimicrobials, such as fluoroquinolones, have …

Purpose Vancomycin-resistant enterococci (VRE) are a leading cause of hospital-acquired
infections with limited therapeutic options. Combination of at least two antimicrobials is a …

Purpose We explored the inhibition ability of linezolid/fosfomycin combination against
biofilms of vancomycin-resistant Enterococcus faecium (VRE fm) and tried to provide a …