Animals live in symbiosis with numerous microbe species. While some can protect hosts
from infection and benefit host health, components of the microbiota or changes to the …

Chemotaxis enables microorganisms to move according to chemical gradients. Although
this process requires substantial cellular energy, it also affords key physiological benefits …

Koch's postulates dictate the use of experimental models to illustrate features of human
disease and provide evidence for a singular organism as the cause. The underlying cause …

To improve our understanding of upper respiratory tract (URT) diseases and the underlying
microbial pathogenesis, a better characterization of the healthy URT microbiome is crucial …

Simple Summary Microorganisms like bacteria, archaea, fungi, microalgae, and viruses
mostly form complex interactive networks within the ecosystem rather than existing as single …

Background Acute otitis media (AOM) is the most common cause of pediatric medical visits
and antibiotic prescriptions worldwide, but its current impact on the US healthcare system is …

It has long been thought that respiratory infections are the direct result of acquisition of
pathogenic viruses or bacteria, followed by their overgrowth, dissemination, and in some …

Chronic obstructive pulmonary disease (COPD) is a debilitating respiratory disease and one
of the leading causes of morbidity and mortality worldwide. It is characterized by persistent …

Abstract Non-typeable Haemophilus influenzae (NTHi) is the most common bacterial cause
of infection of the lower airways in adults with chronic obstructive pulmonary disease …

Under normal physiological conditions, the lung remains an oxygen rich environment.
However, prominent regions of hypoxia are a common feature of infected and inflamed …