Cancer immunotherapy is an emerging treatment strategy that modulates the immune
system to fight against cancer. Although several immunotherapeutic agents have been …

Chimeric antigen receptor T (CAR-T) cell therapy is a promising and precise targeted
therapy for cancer that has demonstrated notable potential in clinical applications. However …

Optogenetic technologies have transformed our ability to precisely control biological
processes in time and space. Yet, current eukaryotic optogenetic systems are limited by …

Glioma is the most common intracranial primary malignancy, with limited treatment options
and a poor overall survival (OS). Immunotherapy has been used successfully in various …

The l-arabinose-responsive AraC and its cognate PBAD promoter underlie one of the most
often used chemically inducible prokaryotic gene expression systems in microbiology and …

Immunotherapies have shown considerable efficacy for the treatment of various cancers, but
a multitude of patients remain unresponsive for various reasons, including poor homing of T …

Optogenetics combines light and genetics to enable precise control of living cells, tissues,
and organisms with tailored functions. Optogenetics has the advantages of …

Tumors originate from a number of genetic events that deregulate homeostatic mechanisms
controlling normal cell behavior. The immune system, devoted to patrol the organism against …

The ability to remote control the expression of therapeutic genes in mammalian cells in order
to treat disease is a central goal of synthetic biology‐inspired therapeutic strategies …

Microbial opsin-based optogenetic tools have been transformative for neuroscience. To
extend optogenetic approaches to the immune system to remotely control immune …