• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Background: The American Heart Association has sponsored both guidelines and scientific
statements that address the diagnosis, management, and prevention of infective …

Background There is pressing need to improve hospital-based addiction care. Various
models for integrating substance use disorder care into hospital settings exist, but there is no …

The incidence of injection drug use–associated infective endocarditis has been increasing
rapidly over the last decade. Patients with drug use–associated infective endocarditis …

Importance Medications for opioid use disorder (MOUD) are highly effective, but only 22% of
individuals in the US with opioid use disorder receive them. Hospitalization potentially …

Objectives The COVID-19 pandemic led to the closure of the IDEA syringe services program
medical student-run free clinic in Miami, Florida. In an effort to continue to serve the …

The opioid overdose epidemic is one of the leading causes of death in adults. 1 Its
devastating effects have included not only a burgeoning overdose crisis but also multiple …

This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Physicians generally recommend that patients resuscitated with naloxone after opioid
overdose stay in the emergency department for a period of observation in order to prevent …

The evolving nature of the opioid epidemic and continued increases in overdose deaths
highlight a need for fundamental change in the collection and use of surveillance data to link …