Roadmap on computational methods in optical imaging and holography

J Rosen, S Alford, B Allan, V Anand, S Arnon… - Applied Physics B, 2024 - Springer
Computational methods have been established as cornerstones in optical imaging and
holography in recent years. Every year, the dependence of optical imaging and holography …

Optical sectioning methods in three-dimensional bioimaging

J Zhang, W Qiao, R Jin, H Li, H Gong… - Light: Science & …, 2025 - nature.com
In recent advancements in life sciences, optical microscopy has played a crucial role in
acquiring high-quality three-dimensional structural and functional information. However, the …

Maternal organophosphate flame retardant exposure alters the developing mesencephalic dopamine system in fetal rat

AJ Newell, VA Kapps, Y Cai, MR Rai… - Toxicological …, 2023 - academic.oup.com
Organophosphate flame retardants (OPFRs) have become the predominant substitution for
legacy brominated flame retardants but there is concern about their potential developmental …

Deep learning-based adaptive optics for light sheet fluorescence microscopy

MR Rai, C Li, HT Ghashghaei… - Biomedical Optics …, 2023 - opg.optica.org
Light sheet fluorescence microscopy (LSFM) is a high-speed imaging technique that is often
used to image intact tissue-cleared specimens with cellular or subcellular resolution. Like …

COMBINe enables automated detection and classification of neurons and astrocytes in tissue-cleared mouse brains

Y Cai, X Zhang, C Li, HT Ghashghaei… - Cell Reports Methods, 2023 - cell.com
Tissue clearing renders entire organs transparent to accelerate whole-tissue imaging; for
example, with light-sheet fluorescence microscopy. Yet, challenges remain in analyzing the …

[HTML][HTML] Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain

X Zhang, G Xiao, C Johnson, Y Cai, ZK Horowitz… - Iscience, 2023 - cell.com
The epidermal growth factor receptor (EGFR) plays a role in cell proliferation and
differentiation during healthy development and tumor growth; however, its requirement for …

Predicting Choices Driven by Emotional Stimuli Using EEG-Based Analysis and Deep Learning

M Aldayel, A Kharrat, A Al-Nafjan - Applied Sciences, 2023 - mdpi.com
Individual choices and preferences are important factors that impact decision making.
Artificial intelligence can predict decisions by objectively detecting individual choices and …

Quantitative analysis of illumination and detection corrections in adaptive light sheet fluorescence microscopy

MR Rai, C Li, A Greenbaum - Biomedical Optics Express, 2022 - opg.optica.org
Light-sheet fluorescence microscopy (LSFM) is a high-speed, high-resolution and minimally
phototoxic technique for 3D imaging of in vivo and in vitro specimens. LSFM exhibits optical …

Model based optimization for refractive index mismatched light sheet imaging

SJ Sheppard, PT Brown, DP Shepherd - Optics Express, 2024 - opg.optica.org
Selective plane illumination microscopy (SPIM) is an optical sectioning imaging approach
based on orthogonal light pathways for excitation and detection. The excitation pathway has …

Correcting for objective sample refractive index mismatch in extended field of view selective plane illumination microscopy

SJ Sheppard, PT Brown, DP Shepherd - arXiv preprint arXiv:2407.18862, 2024 - arxiv.org
Selective plane illumination microscopy (SPIM) is an optical sectioning imaging approach
based on orthogonal light pathways for excitation and detection. The excitation pathway has …