Understanding the genetic architecture of speciation is a major goal in evolutionary biology.
Hybrid dysfunction is thought to arise most commonly through negative interactions between …

Why do proteins evolve at different rates? Advances in systems biology and genomics have
facilitated a move from studying individual proteins to characterizing global cellular factors …

To study gene evolution across a wide range of organisms, biologists need accurate tools
for multiple sequence alignment of protein families. Obtaining accurate alignments …

Molecular phylogenetic analyses have produced a plethora of controversial hypotheses
regarding the patterns of diversification of non-bilaterian animals. To unravel the causes for …

Mudskippers are amphibious fishes that have developed morphological and physiological
adaptations to match their unique lifestyles. Here we perform whole-genome sequencing of …

Meiosis is essential for the fertility of most eukaryotes and its structures and progression are
conserved across kingdoms. Yet many of its core proteins show evidence of rapid or …

Comparative genomics and systems biology offer unprecedented opportunities for testing
central tenets of evolutionary biology formulated by Darwin in the Origin of Species in 1859 …

Hybrids between species are often characterized by novel gene-expression patterns. A
recent study on allele-specific gene expression in hybrids between species of Drosophila …

Organismic evolution requires that variation at distinct hierarchical levels and attributes be
coherently integrated, often in the face of disparate environmental and genetic pressures. A …

Snakes are a remarkable squamate lineage with unique morphological adaptations,
especially those related to the evolution of vertebrate skeletons, organs, and sensory …