Designing antibodies as therapeutics

PJ Carter, A Rajpal - Cell, 2022 - cell.com
Antibody therapeutics are a large and rapidly expanding drug class providing major health
benefits. We provide a snapshot of current antibody therapeutics including their formats …

Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles

R De, MK Mahata, KT Kim - Advanced Science, 2022 - Wiley Online Library
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

Bioactive peptides from food fermentation: A comprehensive review of their sources, bioactivities, applications, and future development

KF Chai, AYH Voo, WN Chen - Comprehensive Reviews in …, 2020 - Wiley Online Library
Bioactive peptides (BPs) are specific protein fragments that exert various beneficial effects
on human bodies and ultimately influence health, depending on their structural properties …

Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems

DA Subramanian, R Langer, G Traverso - Journal of nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …

Nanocarriers based novel and effective drug delivery system

S Khizar, N Alrushaid, FA Khan, N Zine… - International Journal of …, 2023 - Elsevier
Nanotechnology has ultimately come into the domain of drug delivery. Nanosystems for
delivery of drugs are promptly emerging science utilizing different nanoparticles as carriers …

Current evidence on the bioavailability of food bioactive peptides

L Amigo, B Hernández-Ledesma - Molecules, 2020 - mdpi.com
Food protein-derived bioactive peptides are recognized as valuable ingredients of functional
foods and/or nutraceuticals to promote health and reduce the risk of chronic diseases …

Liposomes for oral delivery of protein and peptide-based therapeutics: Challenges, formulation strategies, and advances

A Jash, A Ubeyitogullari, SSH Rizvi - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Throughout the past decade, there has been a rapid growth in the development of
protein/peptide-based therapeutics. These therapeutics have found widespread applications …

Oral peptide delivery: Challenges and the way ahead

SK Dubey, S Parab, N Dabholkar, M Agrawal… - Drug discovery today, 2021 - Elsevier
Highlights•Oral route of administration is the preferred route for drug delivery.•Dosage form
designing plays an essential role in oral peptide delivery.•Preclinical and clinical aspects of …

Strategies for lactase immobilization and delivery to relieve lactose intolerance

Z Deng, Q Deng, B Li, J Li, S Jung, NJ Cho… - Trends in Food Science & …, 2024 - Elsevier
Background Approximately 70% of adults worldwide are affected by lactose malabsorption.
Symptomatic lactose malabsorption is also known as lactose intolerance characterized by …

Nanofiber-based systems intended for diabetes

H Maleki, K Khoshnevisan, SM Sajjadi-Jazi… - Journal of …, 2021 - Springer
Diabetic mellitus (DM) is the most communal metabolic disease resulting from a defect in
insulin secretion, causing hyperglycemia by promoting the progressive destruction of …