Hyaluronic acid (HA) is a natural polymer, produced endogenously by the human body,
which has unique physicochemical and biological properties, exhibiting desirable …

Osteoarthritis (OA), is a common musculoskeletal disorder that will progressively increase in
older populations and is expected to be the most dominant cause of disability in the world …

Stable integration of hydrogel implants with host tissues is of critical importance to cartilage
tissue engineering. Designing and fabricating hydrogels with high adhesive strength …

Tissue engineering scaffolds with tunable viscoelasticity and adaptability for cell behavior
and fate regulation are highly desired. Here a dynamic interpenetrating polymer network …

Temporomandibular joint osteoarthritis (TMJ OA) is a low-inflammatory disorder with
multifactorial etiology. The aim of this review was to present the current state of knowledge …

Osteoarthritis is the most common degenerative and highly prevalent joint disease,
characterized by progressive loss and destruction of articular cartilage. The damaged …

The hydration lubrication was proposed by Jacob Klein, a famous tribologist, in 2001. The
core of this mechanism is the formation of a strong hydrated layer surrounding polar groups …

Articular cartilage is a remarkable tissue whose sophisticated composition and architecture
allow it to withstand complex stresses within the joint. Once injured, cartilage lacks the …

Acute kidney injury (AKI) is a common pathological process that is globally associated with a
high morbidity and mortality rate. The underlying AKI mechanisms include over-produced …

Drug delivery for osteoarthritis (OA) treatment is a continuous challenge because of their
poor bioavailability and rapid clearance in joints. Intra-articular (IA) drug delivery is a …